Abnormal air-filled spaces in the lung.

J. E. Kuhlman, B. L. Reyes, Ralph H Hruban, Frederic B Askin, Elias Zerhouni, Elliot K Fishman, S. S. Siegelman

Research output: Contribution to journalArticle

Abstract

The authors reviewed the radiographic and computed tomographic (CT) appearances of abnormal air-filled spaces in the lung that develop in response to lung diseases. The major types of these lung diseases include infection, vessel-related or vascular-embolic disorders, bronchiectasis, emphysema, pulmonary fibrosis, adult respiratory distress syndrome and air-block diseases, and unusual disorders of the lung (such as Langerhans cell histiocytosis, Klippel-Trenaunay syndrome, and tracheolaryngeal papillomatosis). After studying the CT scans, conventional radiographs, and medical records of 150 patients with various abnormal air-filled spaces in their lungs and 300 lung specimens and the corresponding high-resolution CT scans, the authors concluded that mechanisms of air-space formation fall into five basic categories: (a) vascular occlusion or ischemic necrosis, (b) dilatation of the bronchi, (c) disruption of the elastic fiber network of the lung, (d) remodeling of the lung architecture and retractile fibrosis, and (e) multifactorial or unknown mechanisms.

Original languageEnglish (US)
Pages (from-to)47-75
Number of pages29
JournalRadiographics : a review publication of the Radiological Society of North America, Inc
Volume13
Issue number1
StatePublished - Jan 1993

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Air
Lung
Lung Diseases
Blood Vessels
Klippel-Trenaunay-Weber Syndrome
Langerhans Cell Histiocytosis
Elastic Tissue
Bronchiectasis
Pulmonary Fibrosis
Adult Respiratory Distress Syndrome
Emphysema
Papilloma
Bronchi
Medical Records
Dilatation
Fibrosis
Necrosis
Infection

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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Abnormal air-filled spaces in the lung. / Kuhlman, J. E.; Reyes, B. L.; Hruban, Ralph H; Askin, Frederic B; Zerhouni, Elias; Fishman, Elliot K; Siegelman, S. S.

In: Radiographics : a review publication of the Radiological Society of North America, Inc, Vol. 13, No. 1, 01.1993, p. 47-75.

Research output: Contribution to journalArticle

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