Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line.

B. Mathey-Prevot, G. Nabel, R. Palacios, D. Baltimore

Research output: Contribution to journalArticlepeer-review

Abstract

Among several tyrosine-protein kinases, only v-abl could abrogate interleukin 3 dependence of a lymphoblastoid cell line; v-src and v-fps proteins gave partial or no interleukin 3 independence, respectively. Lymphokine independence was achieved via a nonautocrine mechanism. Direct involvement of c-myc in this process was not evident.

Original languageEnglish (US)
Pages (from-to)4133-4135
Number of pages3
JournalMolecular and Cellular Biology
Volume6
Issue number11
StatePublished - Nov 1986
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology
  • Genetics
  • Molecular Biology

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