Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line.

B. Mathey-Prevot; G. Nabel; R. Palacios; D. Baltimore

Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line.

B. Mathey-Prevot, G. Nabel, R. Palacios, D. Baltimore

Research output: Contribution to journal › Article › peer-review

Abstract

Among several tyrosine-protein kinases, only v-abl could abrogate interleukin 3 dependence of a lymphoblastoid cell line; v-src and v-fps proteins gave partial or no interleukin 3 independence, respectively. Lymphokine independence was achieved via a nonautocrine mechanism. Direct involvement of c-myc in this process was not evident.

Original language	English (US)
Pages (from-to)	4133-4135
Number of pages	3
Journal	Molecular and Cellular Biology
Volume	6
Issue number	11
State	Published - Nov 1986
Externally published	Yes

ASJC Scopus subject areas

Cell Biology
Genetics
Molecular Biology

Cite this

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title = "Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line.",

abstract = "Among several tyrosine-protein kinases, only v-abl could abrogate interleukin 3 dependence of a lymphoblastoid cell line; v-src and v-fps proteins gave partial or no interleukin 3 independence, respectively. Lymphokine independence was achieved via a nonautocrine mechanism. Direct involvement of c-myc in this process was not evident.",

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AU - Mathey-Prevot, B.

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N2 - Among several tyrosine-protein kinases, only v-abl could abrogate interleukin 3 dependence of a lymphoblastoid cell line; v-src and v-fps proteins gave partial or no interleukin 3 independence, respectively. Lymphokine independence was achieved via a nonautocrine mechanism. Direct involvement of c-myc in this process was not evident.

AB - Among several tyrosine-protein kinases, only v-abl could abrogate interleukin 3 dependence of a lymphoblastoid cell line; v-src and v-fps proteins gave partial or no interleukin 3 independence, respectively. Lymphokine independence was achieved via a nonautocrine mechanism. Direct involvement of c-myc in this process was not evident.

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Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line.

Abstract

ASJC Scopus subject areas

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