Abdominal compartment syndrome contributing to failure of extracorporeal membrane oxygenation in an infant with congenital heart disease and sepsis

Christopher T. McKee, Luca Vricella, Z. Leah Harris, R. Blaine Easley

Research output: Contribution to journalArticle

Abstract

Objective: To provide the first account of extracorporeal membrane oxygenation therapy failure secondary to abdominal compartment syndrome. Design: Case report. Setting: Pediatric intensive care unit. Patient: A 4-month-old infant with cyanotic congenital heart disease and Escherichia coli sepsis developed abdominal distention and venous return failure on extracorporeal membrane oxygenation. Intervention: Emergency cardiac catheterization and atrial septectomy were performed. Main Results: Central venous pressure of 120 mm Hg was measured, confirming the diagnosis of abdominal compartment syndrome. Conclusions: Abdominal compartment syndrome is a life-threatening condition resulting from an increase in intraabdominal pressure that compromises abdominal organ perfusion, pulmonary function, and cardiac output. Mortality rates from abdominal compartment syndrome are as high as 60% in adults and children. This report of an infant with congenital heart disease and E coli sepsis represents the first description of abdominal compartment syndrome that contributed to failure of extracorporeal membrane oxygenation and ultimately death. The pathophysiology, diagnosis, and treatment of abdominal compartment syndrome are also reviewed.

Original languageEnglish (US)
Pages (from-to)180-182
Number of pages3
JournalPediatric Critical Care Medicine
Volume7
Issue number2
DOIs
StatePublished - Mar 2006

Fingerprint

Intra-Abdominal Hypertension
Extracorporeal Membrane Oxygenation
Heart Diseases
Sepsis
Escherichia coli
Pediatric Intensive Care Units
Central Venous Pressure
Cardiac Catheterization
Cardiac Output
Emergencies
Perfusion
Pressure
Lung
Mortality
Therapeutics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Critical Care and Intensive Care Medicine

Cite this

Abdominal compartment syndrome contributing to failure of extracorporeal membrane oxygenation in an infant with congenital heart disease and sepsis. / McKee, Christopher T.; Vricella, Luca; Harris, Z. Leah; Easley, R. Blaine.

In: Pediatric Critical Care Medicine, Vol. 7, No. 2, 03.2006, p. 180-182.

Research output: Contribution to journalArticle

@article{88f4a99334b6409c8bf62e26ae32ee94,
title = "Abdominal compartment syndrome contributing to failure of extracorporeal membrane oxygenation in an infant with congenital heart disease and sepsis",
abstract = "Objective: To provide the first account of extracorporeal membrane oxygenation therapy failure secondary to abdominal compartment syndrome. Design: Case report. Setting: Pediatric intensive care unit. Patient: A 4-month-old infant with cyanotic congenital heart disease and Escherichia coli sepsis developed abdominal distention and venous return failure on extracorporeal membrane oxygenation. Intervention: Emergency cardiac catheterization and atrial septectomy were performed. Main Results: Central venous pressure of 120 mm Hg was measured, confirming the diagnosis of abdominal compartment syndrome. Conclusions: Abdominal compartment syndrome is a life-threatening condition resulting from an increase in intraabdominal pressure that compromises abdominal organ perfusion, pulmonary function, and cardiac output. Mortality rates from abdominal compartment syndrome are as high as 60{\%} in adults and children. This report of an infant with congenital heart disease and E coli sepsis represents the first description of abdominal compartment syndrome that contributed to failure of extracorporeal membrane oxygenation and ultimately death. The pathophysiology, diagnosis, and treatment of abdominal compartment syndrome are also reviewed.",
author = "McKee, {Christopher T.} and Luca Vricella and Harris, {Z. Leah} and Easley, {R. Blaine}",
year = "2006",
month = "3",
doi = "10.1097/01.PCC.0000201001.95499.BE",
language = "English (US)",
volume = "7",
pages = "180--182",
journal = "Pediatric Critical Care Medicine",
issn = "1529-7535",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Abdominal compartment syndrome contributing to failure of extracorporeal membrane oxygenation in an infant with congenital heart disease and sepsis

AU - McKee, Christopher T.

AU - Vricella, Luca

AU - Harris, Z. Leah

AU - Easley, R. Blaine

PY - 2006/3

Y1 - 2006/3

N2 - Objective: To provide the first account of extracorporeal membrane oxygenation therapy failure secondary to abdominal compartment syndrome. Design: Case report. Setting: Pediatric intensive care unit. Patient: A 4-month-old infant with cyanotic congenital heart disease and Escherichia coli sepsis developed abdominal distention and venous return failure on extracorporeal membrane oxygenation. Intervention: Emergency cardiac catheterization and atrial septectomy were performed. Main Results: Central venous pressure of 120 mm Hg was measured, confirming the diagnosis of abdominal compartment syndrome. Conclusions: Abdominal compartment syndrome is a life-threatening condition resulting from an increase in intraabdominal pressure that compromises abdominal organ perfusion, pulmonary function, and cardiac output. Mortality rates from abdominal compartment syndrome are as high as 60% in adults and children. This report of an infant with congenital heart disease and E coli sepsis represents the first description of abdominal compartment syndrome that contributed to failure of extracorporeal membrane oxygenation and ultimately death. The pathophysiology, diagnosis, and treatment of abdominal compartment syndrome are also reviewed.

AB - Objective: To provide the first account of extracorporeal membrane oxygenation therapy failure secondary to abdominal compartment syndrome. Design: Case report. Setting: Pediatric intensive care unit. Patient: A 4-month-old infant with cyanotic congenital heart disease and Escherichia coli sepsis developed abdominal distention and venous return failure on extracorporeal membrane oxygenation. Intervention: Emergency cardiac catheterization and atrial septectomy were performed. Main Results: Central venous pressure of 120 mm Hg was measured, confirming the diagnosis of abdominal compartment syndrome. Conclusions: Abdominal compartment syndrome is a life-threatening condition resulting from an increase in intraabdominal pressure that compromises abdominal organ perfusion, pulmonary function, and cardiac output. Mortality rates from abdominal compartment syndrome are as high as 60% in adults and children. This report of an infant with congenital heart disease and E coli sepsis represents the first description of abdominal compartment syndrome that contributed to failure of extracorporeal membrane oxygenation and ultimately death. The pathophysiology, diagnosis, and treatment of abdominal compartment syndrome are also reviewed.

UR - http://www.scopus.com/inward/record.url?scp=33645551535&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645551535&partnerID=8YFLogxK

U2 - 10.1097/01.PCC.0000201001.95499.BE

DO - 10.1097/01.PCC.0000201001.95499.BE

M3 - Article

VL - 7

SP - 180

EP - 182

JO - Pediatric Critical Care Medicine

JF - Pediatric Critical Care Medicine

SN - 1529-7535

IS - 2

ER -