TY - JOUR
T1 - A VLSI neural monitoring system with ultra-wideband telemetry for awake behaving subjects
AU - Greenwald, Elliot
AU - Mollazadeh, Mohsen
AU - Hu, Charles
AU - Tang, Wei
AU - Culurciello, Eugenio
AU - Thakor, Nitish
N1 - Funding Information:
Manuscript received October 14, 2010; revised February 27, 2011; accepted March 30, 2011. Date of current version May 18, 2011. This work was supported in part by the DARPA REPAIR program under Contract 19GM-1088724, in part by NIH MH062444-065296 and 5T32EB003383-07, ONR 439471 and 396490, and in part by the National Science Foundation 06493449 grants. This paper was recommended by Associate Editor V. Owall.
PY - 2011/4
Y1 - 2011/4
N2 - Long-term monitoring of neuronal activity in awake behaving subjects can provide fundamental information about brain dynamics for neuroscience and neuroengineering applications. Here, we present a miniature, lightweight, and low-power recording system for monitoring neural activity in awake behaving animals. The system integrates two custom designed very-large-scale integrated chips, a neural interface module fabricated in 0.5 \mum complementary metaloxide semiconductor technology and an ultra-wideband transmitter module fabricated in a 0.5 \mu m silicon-on-sapphire (SOS) technology. The system amplifies, filters, digitizes, and transmits 16 channels of neural data at a rate of 1 Mb/s. The entire system, which includes the VLSI circuits, a digital interface board, a battery, and a custom housing, is small and lightweight (24 g) and, thus, can be chronically mounted on small animals. The system consumes 4.8 mA and records continuously for up to 40 h powered by a 3.7-V, 200-mAh rechargeable lithium-ion battery. Experimental benchtop characterizations as well as in vivo multichannel neural recordings from awake behaving rats are presented here.
AB - Long-term monitoring of neuronal activity in awake behaving subjects can provide fundamental information about brain dynamics for neuroscience and neuroengineering applications. Here, we present a miniature, lightweight, and low-power recording system for monitoring neural activity in awake behaving animals. The system integrates two custom designed very-large-scale integrated chips, a neural interface module fabricated in 0.5 \mum complementary metaloxide semiconductor technology and an ultra-wideband transmitter module fabricated in a 0.5 \mu m silicon-on-sapphire (SOS) technology. The system amplifies, filters, digitizes, and transmits 16 channels of neural data at a rate of 1 Mb/s. The entire system, which includes the VLSI circuits, a digital interface board, a battery, and a custom housing, is small and lightweight (24 g) and, thus, can be chronically mounted on small animals. The system consumes 4.8 mA and records continuously for up to 40 h powered by a 3.7-V, 200-mAh rechargeable lithium-ion battery. Experimental benchtop characterizations as well as in vivo multichannel neural recordings from awake behaving rats are presented here.
KW - Biopotential amplifier
KW - digital telemetry
KW - electrocorticogram
KW - electroencephalogram
KW - headmounted systems
KW - local field potentials
KW - micropower instrumentation
KW - neural interface
KW - ultra-wideband telemetry
KW - wireless neural recording
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U2 - 10.1109/TBCAS.2011.2141670
DO - 10.1109/TBCAS.2011.2141670
M3 - Article
C2 - 23851199
AN - SCOPUS:79955835534
SN - 1932-4545
VL - 5
SP - 112
EP - 119
JO - IEEE Transactions on Biomedical Circuits and Systems
JF - IEEE Transactions on Biomedical Circuits and Systems
IS - 2
M1 - 5759105
ER -