Abstract
Background: Observational studies have reported varying results about the association of velamentous cord insertion (VCI) with adverse pregnancy outcomes. Objectives: To evaluate the risk of preterm delivery among singleton pregnancies complicated by VCI. Search strategy: Various databases were searched for English-language articles published up to February, 28, 2017, using keywords including VCI; abnormal placentation; abnormal cord insertions; adverse perinatal outcomes; and preterm birth. Outcome measures included preterm delivery; pre-eclampsia; cesarean delivery; fetal demise in utero (FDIU); and small for gestational age (SGA). Selection criteria: Only studies involving VCI were included in the meta-analysis. Data collection and analysis: Analyses were performed using RevMan version 5.3.5 (The Nordic Cochrane Centre, Copenhagen, Denmark). Main results: There were six studies included in the analysis. The VCI and control groups comprised 16 295 and 1 366 485 women, respectively. An increased incidence of preterm delivery was found for the VCI group compared with the control group (11.8% vs 7.0%; adjusted odds ratio [aOR] 1.95, 95% confidence interval [CI] 1.85-2.04). A diagnosis of VCI was also associated with cesarean delivery (aOR 1.17, 95% CI 1.12-1.23), SGA (aOR 1.93, 95% CI 1.83-2.04), and FDIU (aOR 3.96, 95% CI 3.21-4.89). Conclusion: The presence of VCI was associated with adverse pregnancy outcomes.
| Original language | English (US) |
|---|---|
| Journal | International Journal of Gynecology and Obstetrics |
| DOIs | |
| State | Accepted/In press - Jan 1 2018 |
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Keywords
- Adverse pregnancy outcomes
- Cesarean delivery
- Preterm birth
- Velamentous cord insertion
ASJC Scopus subject areas
- Obstetrics and Gynecology
Cite this
A systematic review and meta-analysis of velamentous cord insertion among singleton pregnancies and the risk of preterm delivery. / de los Reyes, Samantha; Henderson, Janice L; Eke, Ahizechukwu.
In: International Journal of Gynecology and Obstetrics, 01.01.2018.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A systematic review and meta-analysis of velamentous cord insertion among singleton pregnancies and the risk of preterm delivery
AU - de los Reyes, Samantha
AU - Henderson, Janice L
AU - Eke, Ahizechukwu
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Background: Observational studies have reported varying results about the association of velamentous cord insertion (VCI) with adverse pregnancy outcomes. Objectives: To evaluate the risk of preterm delivery among singleton pregnancies complicated by VCI. Search strategy: Various databases were searched for English-language articles published up to February, 28, 2017, using keywords including VCI; abnormal placentation; abnormal cord insertions; adverse perinatal outcomes; and preterm birth. Outcome measures included preterm delivery; pre-eclampsia; cesarean delivery; fetal demise in utero (FDIU); and small for gestational age (SGA). Selection criteria: Only studies involving VCI were included in the meta-analysis. Data collection and analysis: Analyses were performed using RevMan version 5.3.5 (The Nordic Cochrane Centre, Copenhagen, Denmark). Main results: There were six studies included in the analysis. The VCI and control groups comprised 16 295 and 1 366 485 women, respectively. An increased incidence of preterm delivery was found for the VCI group compared with the control group (11.8% vs 7.0%; adjusted odds ratio [aOR] 1.95, 95% confidence interval [CI] 1.85-2.04). A diagnosis of VCI was also associated with cesarean delivery (aOR 1.17, 95% CI 1.12-1.23), SGA (aOR 1.93, 95% CI 1.83-2.04), and FDIU (aOR 3.96, 95% CI 3.21-4.89). Conclusion: The presence of VCI was associated with adverse pregnancy outcomes.
AB - Background: Observational studies have reported varying results about the association of velamentous cord insertion (VCI) with adverse pregnancy outcomes. Objectives: To evaluate the risk of preterm delivery among singleton pregnancies complicated by VCI. Search strategy: Various databases were searched for English-language articles published up to February, 28, 2017, using keywords including VCI; abnormal placentation; abnormal cord insertions; adverse perinatal outcomes; and preterm birth. Outcome measures included preterm delivery; pre-eclampsia; cesarean delivery; fetal demise in utero (FDIU); and small for gestational age (SGA). Selection criteria: Only studies involving VCI were included in the meta-analysis. Data collection and analysis: Analyses were performed using RevMan version 5.3.5 (The Nordic Cochrane Centre, Copenhagen, Denmark). Main results: There were six studies included in the analysis. The VCI and control groups comprised 16 295 and 1 366 485 women, respectively. An increased incidence of preterm delivery was found for the VCI group compared with the control group (11.8% vs 7.0%; adjusted odds ratio [aOR] 1.95, 95% confidence interval [CI] 1.85-2.04). A diagnosis of VCI was also associated with cesarean delivery (aOR 1.17, 95% CI 1.12-1.23), SGA (aOR 1.93, 95% CI 1.83-2.04), and FDIU (aOR 3.96, 95% CI 3.21-4.89). Conclusion: The presence of VCI was associated with adverse pregnancy outcomes.
KW - Adverse pregnancy outcomes
KW - Cesarean delivery
KW - Preterm birth
KW - Velamentous cord insertion
UR - http://www.scopus.com/inward/record.url?scp=85044954189&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85044954189&partnerID=8YFLogxK
U2 - 10.1002/ijgo.12489
DO - 10.1002/ijgo.12489
M3 - Article
C2 - 29572823
AN - SCOPUS:85044954189
JO - International Journal of Gynecology and Obstetrics
JF - International Journal of Gynecology and Obstetrics
SN - 0020-7292
ER -