Abstract
We have assessed whether antigenic proteins associated with small nuclear ribonucleoprotein particles (snRNP) are associated with the nuclear matrix. Immunofluorescence studies showed that a subset of these particles (those reactive with anti-Sm antisera) were associated with the nuclear matrix, while a different set of particles (those reactive with anti-La antisera) were not associated with the nuclear matrix. Immunoprecipitation experiments showed that three specific polypeptide components of the snRNP reactive with the anti-Sm antisera were significantly enriched in nuclear matrix proteins.
Original language | English (US) |
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Pages (from-to) | 1224-1232 |
Number of pages | 9 |
Journal | Biochemical and Biophysical Research Communications |
Volume | 105 |
Issue number | 3 |
DOIs | |
State | Published - Apr 14 1982 |
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Molecular Biology
- Cell Biology