A study of homologous chromosomes using a morphometric approach

H. F.L. Mark; H. E. Wyandt; T. Pan; R. Mark; M. Parmenter; W. Campbell; Y. Mark

doi:10.1139/g93-132

A study of homologous chromosomes using a morphometric approach

H. F.L. Mark, H. E. Wyandt, T. Pan, R. Mark, M. Parmenter, W. Campbell, Y. Mark

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4 Scopus citations

Abstract

A previous study of 100 karyotyped metaphase cells has demonstrated the utility of a graphic arts tool in deriving chromosome measurements for relative length determination. In the present study we utilize this same approach to address the question: 'What are the average differences in relative lengths-between apparently normal homologous chromosomes?' Normal standards derived from this study will be useful for testing specific hypotheses involving heteromorphic differences between homologs. No such data on normal controls could readily be found in either An International System for Human Cytogenetic Nomenclature (1985) or elsewhere.

Original language	English (US)
Pages (from-to)	1003-1006
Number of pages	4
Journal	Genome
Volume	36
Issue number	5
DOIs	https://doi.org/10.1139/g93-132
State	Published - 1993
Externally published	Yes

ASJC Scopus subject areas

Biotechnology
Molecular Biology
Genetics

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AU - Mark, H. F.L.

AU - Wyandt, H. E.

AU - Pan, T.

AU - Mark, R.

AU - Parmenter, M.

AU - Campbell, W.

AU - Mark, Y.

PY - 1993

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AB - A previous study of 100 karyotyped metaphase cells has demonstrated the utility of a graphic arts tool in deriving chromosome measurements for relative length determination. In the present study we utilize this same approach to address the question: 'What are the average differences in relative lengths-between apparently normal homologous chromosomes?' Normal standards derived from this study will be useful for testing specific hypotheses involving heteromorphic differences between homologs. No such data on normal controls could readily be found in either An International System for Human Cytogenetic Nomenclature (1985) or elsewhere.

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VL - 36

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JO - Genome

JF - Genome

IS - 5

ER -

A study of homologous chromosomes using a morphometric approach

Abstract

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