A standardized grading system for scleritis

H. Nida Sen, Amit A. Sangave, Debra A. Goldstein, Eric B. Suhler, Denise Cunningham, Susan Vitale, Robert B. Nussenblatt

Research output: Contribution to journalArticle

Abstract

Objective: This study evaluated the performance of a standardized grading system for scleritis using standard digital photographs. Design: Cross-sectional interobserver agreement study. Participants: Photo archives from the National Eye Institute. Methods: Three uveitis specialists from 3 different centers graded 79 randomly arranged images of the sclera with various degrees of inflammation. Grading was done using standard screen resolution (1024×768 pixels) on a 0 to 4+ scale in 2 sessions: (1) without using reference photographs and (2) with reference to a set of standard photographs (proposed grading system). The graders were masked to the order of images, and the order of images was randomized. Interobserver agreement in grading the severity of inflammation with and without the use of grading system was evaluated. Main Outcome Measures: Interobserver agreement. Results: The proposed grading system for assessing activity in scleritis demonstrated a good interobserver agreement. Interobserver agreement (pooled κ) was poor (0.289) without photographic guidance and improved substantially when the "grading system" with standardized photographs was used (κ = 0.603). Conclusions: This system of standardized images for scleritis grading provides significantly more consistent grading of scleral inflammation in this study and has clear applications in clinical settings and clinical research. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references.

Original languageEnglish (US)
Pages (from-to)768-771
Number of pages4
JournalOphthalmology
Volume118
Issue number4
DOIs
StatePublished - Apr 2011
Externally publishedYes

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Scleritis
Disclosure
Inflammation
National Eye Institute (U.S.)
Sclera
Uveitis
Outcome Assessment (Health Care)
Research

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Sen, H. N., Sangave, A. A., Goldstein, D. A., Suhler, E. B., Cunningham, D., Vitale, S., & Nussenblatt, R. B. (2011). A standardized grading system for scleritis. Ophthalmology, 118(4), 768-771. https://doi.org/10.1016/j.ophtha.2010.08.027

A standardized grading system for scleritis. / Sen, H. Nida; Sangave, Amit A.; Goldstein, Debra A.; Suhler, Eric B.; Cunningham, Denise; Vitale, Susan; Nussenblatt, Robert B.

In: Ophthalmology, Vol. 118, No. 4, 04.2011, p. 768-771.

Research output: Contribution to journalArticle

Sen, HN, Sangave, AA, Goldstein, DA, Suhler, EB, Cunningham, D, Vitale, S & Nussenblatt, RB 2011, 'A standardized grading system for scleritis', Ophthalmology, vol. 118, no. 4, pp. 768-771. https://doi.org/10.1016/j.ophtha.2010.08.027
Sen HN, Sangave AA, Goldstein DA, Suhler EB, Cunningham D, Vitale S et al. A standardized grading system for scleritis. Ophthalmology. 2011 Apr;118(4):768-771. https://doi.org/10.1016/j.ophtha.2010.08.027
Sen, H. Nida ; Sangave, Amit A. ; Goldstein, Debra A. ; Suhler, Eric B. ; Cunningham, Denise ; Vitale, Susan ; Nussenblatt, Robert B. / A standardized grading system for scleritis. In: Ophthalmology. 2011 ; Vol. 118, No. 4. pp. 768-771.
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