A SPECT camera for simultaneous SPECT/MRI

Dirk Meier, Douglas J. Wagenaar, Gunnar Mæhlum, Bjørn Sundal, Bradley E. Patt, Si Chen, Jingyan Xu, Jianhua Yu, Benjamin M.W. Tsui, Mark Hamamura, Werner W. Roeck, Seung Hoon Ha, Orhan Nalcioglu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We describe a single photon emission computed tomograph (SPECT) which can be operated inside state-of-the-art magnetic resonance imaging (MRI) systems. The combined SPECT/MRI system allows one to acquire simultaneously the data from both modalities and co-register the images in space and time. The new SPECT is based on the semiconductor cadmium zinc telluride (CZT) and application specific integrated circuits (ASICs) - two technologies which are MR-compatible and almost insensitive to magnetic fields. The SPECT camera has an energy resolution of 5.4 keV full-width-half-maximum (FWHM) at the 140-keV photo peak from 99mTc for either inside or outside of the MRI. We acquired the first SPECT and MR images from resolution phantoms and mice in-vivo. The experiments show that the MRI is minimally affected by the SPECT camera inside the bore. Preliminary results for the SPECT camera show high sensitivity of about 1.6% and a spatial resolution of 4 mm FWHM.

Original languageEnglish (US)
Title of host publication2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009
Pages2313-2318
Number of pages6
DOIs
StatePublished - 2009
Event2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009 - Orlando, FL, United States
Duration: Oct 25 2009Oct 31 2009

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Other

Other2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009
CountryUnited States
CityOrlando, FL
Period10/25/0910/31/09

Keywords

  • CZT
  • Dynamic imaging
  • MRI
  • Molecular imaging
  • Multi-modality imaging
  • SPECT

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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