Abstract
We describe a single photon emission computed tomograph (SPECT) which can be operated inside state-of-the-art magnetic resonance imaging (MRI) systems. The combined SPECT/MRI system allows one to acquire simultaneously the data from both modalities and co-register the images in space and time. The new SPECT is based on the semiconductor cadmium zinc telluride (CZT) and application specific integrated circuits (ASICs) - two technologies which are MR-compatible and almost insensitive to magnetic fields. The SPECT camera has an energy resolution of 5.4 keV full-width-half-maximum (FWHM) at the 140-keV photo peak from 99mTc for either inside or outside of the MRI. We acquired the first SPECT and MR images from resolution phantoms and mice in-vivo. The experiments show that the MRI is minimally affected by the SPECT camera inside the bore. Preliminary results for the SPECT camera show high sensitivity of about 1.6% and a spatial resolution of 4 mm FWHM.
| Original language | English (US) |
|---|---|
| Title of host publication | IEEE Nuclear Science Symposium Conference Record |
| Pages | 2313-2318 |
| Number of pages | 6 |
| DOIs | |
| State | Published - 2009 |
| Event | 2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009 - Orlando, FL, United States Duration: Oct 25 2009 → Oct 31 2009 |
Other
| Other | 2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009 |
|---|---|
| Country | United States |
| City | Orlando, FL |
| Period | 10/25/09 → 10/31/09 |
Fingerprint
Keywords
- CZT
- Dynamic imaging
- Molecular imaging
- MRI
- Multi-modality imaging
- SPECT
ASJC Scopus subject areas
- Radiation
- Nuclear and High Energy Physics
- Radiology Nuclear Medicine and imaging
Cite this
A SPECT camera for simultaneous SPECT/MRI. / Meier, Dirk; Wagenaar, Douglas J.; Mæhlum, Gunnar; Sundal, Bjørn; Patt, Bradley E.; Chen, Si; Xu, Jingyan; Yu, Jianhua; Tsui, Benjamin; Hamamura, Mark; Roeck, Werner W.; Ha, Seung Hoon; Nalcioglu, Orhan.
IEEE Nuclear Science Symposium Conference Record. 2009. p. 2313-2318 5402269.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - A SPECT camera for simultaneous SPECT/MRI
AU - Meier, Dirk
AU - Wagenaar, Douglas J.
AU - Mæhlum, Gunnar
AU - Sundal, Bjørn
AU - Patt, Bradley E.
AU - Chen, Si
AU - Xu, Jingyan
AU - Yu, Jianhua
AU - Tsui, Benjamin
AU - Hamamura, Mark
AU - Roeck, Werner W.
AU - Ha, Seung Hoon
AU - Nalcioglu, Orhan
PY - 2009
Y1 - 2009
N2 - We describe a single photon emission computed tomograph (SPECT) which can be operated inside state-of-the-art magnetic resonance imaging (MRI) systems. The combined SPECT/MRI system allows one to acquire simultaneously the data from both modalities and co-register the images in space and time. The new SPECT is based on the semiconductor cadmium zinc telluride (CZT) and application specific integrated circuits (ASICs) - two technologies which are MR-compatible and almost insensitive to magnetic fields. The SPECT camera has an energy resolution of 5.4 keV full-width-half-maximum (FWHM) at the 140-keV photo peak from 99mTc for either inside or outside of the MRI. We acquired the first SPECT and MR images from resolution phantoms and mice in-vivo. The experiments show that the MRI is minimally affected by the SPECT camera inside the bore. Preliminary results for the SPECT camera show high sensitivity of about 1.6% and a spatial resolution of 4 mm FWHM.
AB - We describe a single photon emission computed tomograph (SPECT) which can be operated inside state-of-the-art magnetic resonance imaging (MRI) systems. The combined SPECT/MRI system allows one to acquire simultaneously the data from both modalities and co-register the images in space and time. The new SPECT is based on the semiconductor cadmium zinc telluride (CZT) and application specific integrated circuits (ASICs) - two technologies which are MR-compatible and almost insensitive to magnetic fields. The SPECT camera has an energy resolution of 5.4 keV full-width-half-maximum (FWHM) at the 140-keV photo peak from 99mTc for either inside or outside of the MRI. We acquired the first SPECT and MR images from resolution phantoms and mice in-vivo. The experiments show that the MRI is minimally affected by the SPECT camera inside the bore. Preliminary results for the SPECT camera show high sensitivity of about 1.6% and a spatial resolution of 4 mm FWHM.
KW - CZT
KW - Dynamic imaging
KW - Molecular imaging
KW - MRI
KW - Multi-modality imaging
KW - SPECT
UR - http://www.scopus.com/inward/record.url?scp=77951199405&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77951199405&partnerID=8YFLogxK
U2 - 10.1109/NSSMIC.2009.5402269
DO - 10.1109/NSSMIC.2009.5402269
M3 - Conference contribution
AN - SCOPUS:77951199405
SN - 9781424439621
SP - 2313
EP - 2318
BT - IEEE Nuclear Science Symposium Conference Record
ER -