A SPECT camera for simultaneous SPECT/MRI

Dirk Meier; Douglas J. Wagenaar; Gunnar Mæhlum; Bjørn Sundal; Bradley E. Patt; Si Chen; Jingyan Xu; Jianhua Yu; Benjamin M.W. Tsui; Mark Hamamura; Werner W. Roeck; Seung Hoon Ha; Orhan Nalcioglu

doi:10.1109/NSSMIC.2009.5402269

A SPECT camera for simultaneous SPECT/MRI

Dirk Meier, Douglas J. Wagenaar, Gunnar Mæhlum, Bjørn Sundal, Bradley E. Patt, Si Chen, Jingyan Xu, Jianhua Yu, Benjamin M.W. Tsui, Mark Hamamura, Werner W. Roeck, Seung Hoon Ha, Orhan Nalcioglu

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We describe a single photon emission computed tomograph (SPECT) which can be operated inside state-of-the-art magnetic resonance imaging (MRI) systems. The combined SPECT/MRI system allows one to acquire simultaneously the data from both modalities and co-register the images in space and time. The new SPECT is based on the semiconductor cadmium zinc telluride (CZT) and application specific integrated circuits (ASICs) - two technologies which are MR-compatible and almost insensitive to magnetic fields. The SPECT camera has an energy resolution of 5.4 keV full-width-half-maximum (FWHM) at the 140-keV photo peak from ^99mTc for either inside or outside of the MRI. We acquired the first SPECT and MR images from resolution phantoms and mice in-vivo. The experiments show that the MRI is minimally affected by the SPECT camera inside the bore. Preliminary results for the SPECT camera show high sensitivity of about 1.6% and a spatial resolution of 4 mm FWHM.

Original language	English (US)
Title of host publication	2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009
Pages	2313-2318
Number of pages	6
DOIs	https://doi.org/10.1109/NSSMIC.2009.5402269
State	Published - 2009
Event	2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009 - Orlando, FL, United States Duration: Oct 25 2009 → Oct 31 2009

Publication series

Name	IEEE Nuclear Science Symposium Conference Record
ISSN (Print)	1095-7863

Other

Other	2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009
Country	United States
City	Orlando, FL
Period	10/25/09 → 10/31/09

Keywords

CZT
Dynamic imaging
MRI
Molecular imaging
Multi-modality imaging
SPECT

ASJC Scopus subject areas

Radiation
Nuclear and High Energy Physics
Radiology Nuclear Medicine and imaging

Access to Document

10.1109/NSSMIC.2009.5402269

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Meier, D., Wagenaar, D. J., Mæhlum, G., Sundal, B., Patt, B. E., Chen, S., Xu, J., Yu, J., Tsui, B. M. W., Hamamura, M., Roeck, W. W., Ha, S. H., & Nalcioglu, O. (2009). A SPECT camera for simultaneous SPECT/MRI. In 2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009 (pp. 2313-2318). [5402269] (IEEE Nuclear Science Symposium Conference Record). https://doi.org/10.1109/NSSMIC.2009.5402269

A SPECT camera for simultaneous SPECT/MRI. / Meier, Dirk; Wagenaar, Douglas J.; Mæhlum, Gunnar; Sundal, Bjørn; Patt, Bradley E.; Chen, Si; Xu, Jingyan; Yu, Jianhua; Tsui, Benjamin M.W.; Hamamura, Mark; Roeck, Werner W.; Ha, Seung Hoon; Nalcioglu, Orhan.

2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009. 2009. p. 2313-2318 5402269 (IEEE Nuclear Science Symposium Conference Record).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Meier, D, Wagenaar, DJ, Mæhlum, G, Sundal, B, Patt, BE, Chen, S, Xu, J, Yu, J, Tsui, BMW, Hamamura, M, Roeck, WW, Ha, SH & Nalcioglu, O 2009, A SPECT camera for simultaneous SPECT/MRI. in 2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009., 5402269, IEEE Nuclear Science Symposium Conference Record, pp. 2313-2318, 2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009, Orlando, FL, United States, 10/25/09. https://doi.org/10.1109/NSSMIC.2009.5402269

Meier, Dirk ; Wagenaar, Douglas J. ; Mæhlum, Gunnar ; Sundal, Bjørn ; Patt, Bradley E. ; Chen, Si ; Xu, Jingyan ; Yu, Jianhua ; Tsui, Benjamin M.W. ; Hamamura, Mark ; Roeck, Werner W. ; Ha, Seung Hoon ; Nalcioglu, Orhan. / A SPECT camera for simultaneous SPECT/MRI. 2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009. 2009. pp. 2313-2318 (IEEE Nuclear Science Symposium Conference Record).

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AB - We describe a single photon emission computed tomograph (SPECT) which can be operated inside state-of-the-art magnetic resonance imaging (MRI) systems. The combined SPECT/MRI system allows one to acquire simultaneously the data from both modalities and co-register the images in space and time. The new SPECT is based on the semiconductor cadmium zinc telluride (CZT) and application specific integrated circuits (ASICs) - two technologies which are MR-compatible and almost insensitive to magnetic fields. The SPECT camera has an energy resolution of 5.4 keV full-width-half-maximum (FWHM) at the 140-keV photo peak from 99mTc for either inside or outside of the MRI. We acquired the first SPECT and MR images from resolution phantoms and mice in-vivo. The experiments show that the MRI is minimally affected by the SPECT camera inside the bore. Preliminary results for the SPECT camera show high sensitivity of about 1.6% and a spatial resolution of 4 mm FWHM.

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