TY - GEN
T1 - A simultaneous neural recording and stimulation system using signal folding in recording circuits
AU - Chen, Yi
AU - Basu, Arindam
AU - Liu, Xu
AU - Yao, Lei
AU - Nag, Sudip
AU - Je, Minkyu
AU - Thakor, Nitish
N1 - Funding Information:
Financial support from Singapore MOE through project RG 87/16 is acknowledged.
Publisher Copyright:
© 2017 IEEE.
PY - 2017/7/2
Y1 - 2017/7/2
N2 - A closed-loop brain-machine interface requires the integration of the neural stimulation and recording circuits with the microelectrode array. A challenge for simultaneous neural recording and stimulation is the large interference faced by the neural amplifier induced by stimulation artifacts. In this work, front-end circuit design technique and digital post-processing are combined to provide a solution for fast recovery of the neural amplifier from artifact, based on a signal folding scheme. A chip integrating the neural recording and stimulation circuits is implemented in GF-0.18μm CMOS process for proof of concept. In - vitro experiment is conducted using this chip, showing the viability of the proposed design. At stimulation current levels from 50 - 100 μA, which is sufficient for deep brain stimulation, a faster recovery time of around 1 ms is achieved with the proposed neural amplifier compared to 4 ms from conventional one.
AB - A closed-loop brain-machine interface requires the integration of the neural stimulation and recording circuits with the microelectrode array. A challenge for simultaneous neural recording and stimulation is the large interference faced by the neural amplifier induced by stimulation artifacts. In this work, front-end circuit design technique and digital post-processing are combined to provide a solution for fast recovery of the neural amplifier from artifact, based on a signal folding scheme. A chip integrating the neural recording and stimulation circuits is implemented in GF-0.18μm CMOS process for proof of concept. In - vitro experiment is conducted using this chip, showing the viability of the proposed design. At stimulation current levels from 50 - 100 μA, which is sufficient for deep brain stimulation, a faster recovery time of around 1 ms is achieved with the proposed neural amplifier compared to 4 ms from conventional one.
UR - http://www.scopus.com/inward/record.url?scp=85050030802&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85050030802&partnerID=8YFLogxK
U2 - 10.1109/BIOCAS.2017.8325190
DO - 10.1109/BIOCAS.2017.8325190
M3 - Conference contribution
AN - SCOPUS:85050030802
T3 - 2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings
SP - 1
EP - 4
BT - 2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017
Y2 - 19 October 2017 through 21 October 2017
ER -