A simplified technique of small intestinal transplantation in the rat

Richard P. Harmel

Research output: Contribution to journalArticlepeer-review

Abstract

A technique is described of experimental intestinal transplantation in the rat in which, using microsurgical technique, the superior mesenteric artery and vein distal to the right colic artery are dissected free. The ends of the supplied bowel segment are divided and the lumen irrigated with 0.5% neomycin. The divided superior mesenteric artery is perfused with iced heparinized lactated Ringer's solution, the vessels are then anastomosed to the recipient's aorta and inferior vena cava in end-to-side fashion, and the bowel ends are exteriorized as cutaneous stomas. Seven of 13 recipients of syngeneic grafts survived, and grafts were patent though atrophic up to 12 months later.

Original languageEnglish (US)
Pages (from-to)400-403
Number of pages4
JournalJournal of pediatric surgery
Volume19
Issue number4
DOIs
StatePublished - Aug 1984

Keywords

  • Intestinal transplantation

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health

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