A simplified route to a key intermediate in the synthesis of the chinese nootropic agent huperzine a

Alan P. Kozikowski; E. Rajarathnam Reddy; Chris P. Miller

A simplified route to a key intermediate in the synthesis of the chinese nootropic agent huperzine a

Alan P. Kozikowski, E. Rajarathnam Reddy, Chris P. Miller

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

An efficient one-pot three-component process for the preparation of 2-pyridones from a carbonyl compound, ammonia, and methyl propiolate has been found which provides ready access to a key intermediate in the synthesis of huperzine A.

Original language	English (US)
Pages (from-to)	195-197
Number of pages	3
Journal	Journal of the Chemical Society, Perkin Transactions 1
Issue number	1
State	Published - Dec 1 1990

ASJC Scopus subject areas

Chemistry(all)

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title = "A simplified route to a key intermediate in the synthesis of the chinese nootropic agent huperzine a",

abstract = "An efficient one-pot three-component process for the preparation of 2-pyridones from a carbonyl compound, ammonia, and methyl propiolate has been found which provides ready access to a key intermediate in the synthesis of huperzine A.",

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year = "1990",

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T1 - A simplified route to a key intermediate in the synthesis of the chinese nootropic agent huperzine a

AU - Kozikowski, Alan P.

AU - Rajarathnam Reddy, E.

AU - Miller, Chris P.

PY - 1990/12/1

Y1 - 1990/12/1

N2 - An efficient one-pot three-component process for the preparation of 2-pyridones from a carbonyl compound, ammonia, and methyl propiolate has been found which provides ready access to a key intermediate in the synthesis of huperzine A.

AB - An efficient one-pot three-component process for the preparation of 2-pyridones from a carbonyl compound, ammonia, and methyl propiolate has been found which provides ready access to a key intermediate in the synthesis of huperzine A.

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JO - Journal of the Chemical Society, Perkin Transactions 1

JF - Journal of the Chemical Society, Perkin Transactions 1

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