A simple model of the hemodynamic effects of a proximal coronary artery narrowing

E. H. Klopp, Vincent L Gott

Research output: Contribution to journalArticle

Abstract

A simple mathematical model of the hemodynamic effects of a discrete proximal coronary artery obstruction is presented. The model demonstrates that resting myocardial flow demands fail to be met when the vessel diameter is decreased by 75% or greater. More strikingly, it shows that the maximum flow obtainable for increased myocardial oxygen demand begins to fall significantly with a lesion causing a 40 to 50% obstruction. The implications of these findings in relation to stress induced angina are discussed.

Original languageEnglish (US)
Pages (from-to)309-312
Number of pages4
JournalAnnals of Thoracic Surgery
Volume19
Issue number3
StatePublished - 1975

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Coronary Vessels
Theoretical Models
Hemodynamics
Oxygen

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

A simple model of the hemodynamic effects of a proximal coronary artery narrowing. / Klopp, E. H.; Gott, Vincent L.

In: Annals of Thoracic Surgery, Vol. 19, No. 3, 1975, p. 309-312.

Research output: Contribution to journalArticle

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