A simple, inexpensive method of monitoring brain temperature in conscious rodents

Kenneth H. Neill, Barbara J. Crain, J. Victor Nadler

Research output: Contribution to journalArticlepeer-review

Abstract

A method was developed to monitor brain temperature in conscious, unrestrained rodents. A commercially available thermocouple microprobe was modified so that it could be screwed firmly into a guide cannula that had been stereotactically implanted in the brain. Because the microprobe remains firmly in place, it is possible to record continuously for several hours from a single animal. Because the microprobe is easily removed, one can also record intermittently from several animals at once. The necessary equipment is relatively inexpensive and the modified microprobe can be sterilized and reused indefinitely. This method has proved especially useful for monitoring brain temperature during and after transient cerebral ischemia, an insult that destroys CNS neurons in a temperature-sensitive fashion.

Original languageEnglish (US)
Pages (from-to)179-183
Number of pages5
JournalJournal of Neuroscience Methods
Volume33
Issue number2-3
DOIs
StatePublished - Aug 1990

Keywords

  • Brain temperature
  • Cerebral ischemia

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint

Dive into the research topics of 'A simple, inexpensive method of monitoring brain temperature in conscious rodents'. Together they form a unique fingerprint.

Cite this