A short, simple and general approach for the synthesis of (3S,4S)-3-methoxy-4-methylamino pyrrolidine and (3S,4R)-3-methoxy-4-methylamino pyrrolidine

A. Ravi Kumar; J. Santhosh Reddy; B. Venkateswara Rao

doi:10.1016/S0040-4039(03)01362-5

A short, simple and general approach for the synthesis of (3S,4S)-3-methoxy-4-methylamino pyrrolidine and (3S,4R)-3-methoxy-4-methylamino pyrrolidine

A. Ravi Kumar, J. Santhosh Reddy, B. Venkateswara Rao

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

A general and efficient stereoselective approach for the synthesis of (3S,4S) and (3S,4R)-3-methoxy-4-methylamino pyrrolidines, a part of the structure of AG-7352, a naphthyridine antitumor agent and quinoline antibacterial compounds has been described.

Original language	English (US)
Pages (from-to)	5687-5689
Number of pages	3
Journal	Tetrahedron Letters
Volume	44
Issue number	30
DOIs	https://doi.org/10.1016/S0040-4039(03)01362-5
State	Published - Jul 21 2003
Externally published	Yes

Keywords

Amino ditosylated compounds
Chiral pyrrolidines
Regioselective cyclization
S displacement

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(03)01362-5

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abstract = "A general and efficient stereoselective approach for the synthesis of (3S,4S) and (3S,4R)-3-methoxy-4-methylamino pyrrolidines, a part of the structure of AG-7352, a naphthyridine antitumor agent and quinoline antibacterial compounds has been described.",

keywords = "Amino ditosylated compounds, Chiral pyrrolidines, Regioselective cyclization, S displacement",

author = "Kumar, {A. Ravi} and Reddy, {J. Santhosh} and Rao, {B. Venkateswara}",

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T1 - A short, simple and general approach for the synthesis of (3S,4S)-3-methoxy-4-methylamino pyrrolidine and (3S,4R)-3-methoxy-4-methylamino pyrrolidine

AU - Kumar, A. Ravi

AU - Reddy, J. Santhosh

AU - Rao, B. Venkateswara

PY - 2003/7/21

Y1 - 2003/7/21

N2 - A general and efficient stereoselective approach for the synthesis of (3S,4S) and (3S,4R)-3-methoxy-4-methylamino pyrrolidines, a part of the structure of AG-7352, a naphthyridine antitumor agent and quinoline antibacterial compounds has been described.

AB - A general and efficient stereoselective approach for the synthesis of (3S,4S) and (3S,4R)-3-methoxy-4-methylamino pyrrolidines, a part of the structure of AG-7352, a naphthyridine antitumor agent and quinoline antibacterial compounds has been described.

KW - Amino ditosylated compounds

KW - Chiral pyrrolidines

KW - Regioselective cyclization

KW - S displacement

UR - http://www.scopus.com/inward/record.url?scp=0038505296&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0038505296&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(03)01362-5

DO - 10.1016/S0040-4039(03)01362-5

M3 - Article

AN - SCOPUS:0038505296

SN - 0040-4039

VL - 44

SP - 5687

EP - 5689

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 30

ER -

A short, simple and general approach for the synthesis of (3S,4S)-3-methoxy-4-methylamino pyrrolidine and (3S,4R)-3-methoxy-4-methylamino pyrrolidine

Abstract

Keywords

ASJC Scopus subject areas

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