@inproceedings{604928dbf9f14cfabd7239224b90975c,
title = "A robust energy minimization algorithm for MS-lesion segmentation",
abstract = "The detection of multiple sclerosis lesion is important for many neuroimaging studies. In this paper, a new automatic robust algorithm for lesion segmentation based on MR images is proposed. This method takes full advantage of the decomposition of MR images into the true image that characterizes a physical property of the tissues and the bias field that accounts for the intensity inhomogeneity. An energy function is defined in term of the property of true image and bias field. The energy minimization is proposed for seeking the optimal segmentation result of lesions and white matter. Then postprocessing operations is used to select the most plausible lesions in the obtained hyperintense signals. The experimental results show that our approach is effective and robust for the lesion segmentation.",
keywords = "Bias field, Energy minimization, MR, Multiple sclerosis lesion, True image",
author = "Zhaoxuan Gong and Dazhe Zhao and Chunming Li and Wenjun Tan and Christos Davatzikos",
note = "Funding Information: This research was partly supported by National Natural Science Foundation of China(NSFC) under Grant No. 61302012 and No. 61172002, the Fundamental Research Funds for the Central Universities under Grant N130418002 and N120518001, and Liaoning Natural Science Foundation under Grant No. 2013020021. Publisher Copyright: {\textcopyright} Springer International Publishing Switzerland 2015; 11th International Symposium on Advances in Visual Computing, ISVC 2015 ; Conference date: 14-12-2015 Through 16-12-2015",
year = "2015",
doi = "10.1007/978-3-319-27857-5_47",
language = "English (US)",
isbn = "9783319278568",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer Verlag",
pages = "521--530",
editor = "Mark Elendt and Richard Boyle and Eric Ragan and Bahram Parvin and Rogerio Feris and Tim McGraw and Ioannis Pavlidis and Regis Kopper and George Bebis and Darko Koracin and Zhao Ye and Gunther Weber",
booktitle = "Advances in Visual Computing - 11th International Symposium, ISVC 2015, Proceedings",
}