A review of the evidence from family, twin and adoption studies for a genetic contribution to adult psychiatric disorders

Regina A. Shih, Pamela L. Belmonte, Peter P. Zandi

Research output: Contribution to journalReview article

Abstract

Family, twin and adoption studies have provided major evidence for the role of genetics in numerous psychiatric disorders including obsessive-compulsive disorder, panic disorder, major depressive disorder, bipolar disorder, schizophrenia and Alzheimer's disease. As the search for patterns of inheritance and candidate genes of these complex disorders continues, we review relevant findings from quantitative genetic studies and outline the main challenges for the field of psychiatric genetics to focus on in order to more definitively establish the underpinnings of genetic and environmental influences of adult psychopathology.

Original languageEnglish (US)
Pages (from-to)260-283
Number of pages24
JournalInternational Review of Psychiatry
Volume16
Issue number4
DOIs
StatePublished - Nov 1 2004

ASJC Scopus subject areas

  • Psychiatry and Mental health

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