A review of repetitive transcranial magnetic stimulation for adolescents with treatment-resistant depression

Leela R. Magavi, Irving M. Reti, Roma A. Vasa

Research output: Contribution to journalReview articlepeer-review

Abstract

This review examines the efficacy and safety of repetitive transcranial magnetic stimulation (rTMS) as a treatment for treatment-resistant depression in adolescents. A systematic review of six databases was conducted. Ten multi-subject trials, all uncontrolled, and five case reports met inclusion criteria. Twelve studies focused on treatment efficacy, whereas three studies focused exclusively on adverse events. All efficacy studies focused on adolescents only; 10 of these studies indicated that rTMS may demonstrate some benefit. Improvement within 2–8 weeks was reported in most studies, with a few studies indicating potential long-term benefits. A variety of adverse events occurred including scalp pain, which was the most common, as well as seizures. Controlled studies of rTMS are warranted to further examine whether this treatment is a potential option for adolescents with treatment-resistant depression.

Original languageEnglish (US)
Pages (from-to)79-88
Number of pages10
JournalInternational Review of Psychiatry
Volume29
Issue number2
DOIs
StatePublished - Mar 4 2017

Keywords

  • Depression
  • paediatric
  • repetitive transcranial magnetic stimulation

ASJC Scopus subject areas

  • Psychiatry and Mental health

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