A review for clinical outcomes research: Hypothesis generation, data strategy, and hypothesis-driven statistical analysis

David C. Chang, Mark A. Talamini

Research output: Contribution to journalArticlepeer-review

Abstract

In recent years, more and more large, population-level databases have become available for clinical research. The size and complexity of these databases often present a methodological challenge for investigators. We propose that a "protocol" may facilitate the research process using these databases. In addition, much like the structured History and Physical (H&P) helps the audience appreciate the details of a patient case more systematically, a formal outcomes research protocol can also help in the systematic evaluation of an outcomes research manuscript.

Original languageEnglish (US)
Pages (from-to)2254-2260
Number of pages7
JournalSurgical endoscopy
Volume25
Issue number7
DOIs
StatePublished - Jul 2011

Keywords

  • Clinical papers
  • Education
  • Research
  • Trials

ASJC Scopus subject areas

  • Surgery

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