A report on brain tumors from a retrospective cohort study of refinery workers

C. P. Wen, S. P. Tsai, R. L. Gibson

Research output: Contribution to journalArticlepeer-review

Abstract

In the present study of 30 brain tumor cases, at least 6 cases show equivocal diagnoses, even as they appeared on the death certificates. They are: 1 case of malignant melanoma, 3 cases of metastatic (adeno)carcinoma or neuroblastoma, 1 case of possible brain tumor, and 1 case of cerebrovascular accident due to possible brain tumor. Clinical and/or pathological review of these brain tumors would be necessary to establish their true classification. Some 'artifacts' have also arisen from variations in the rules of selection for cancer among the different revisions of ICD coding. For example, if the 9th Revision was used instead of the 8th, several of the brain cancers listed would no longer be classified as cancer of the brain. In addition to the retrospective studies, this refinery is participating in a morbidity study, a prospective mortality study, and a tumor registry. The tumor registry and mortality study record all newly diagnosed cancer in the active employees and all deaths in the employees and annuitants. The institution of this registry began in 1977 in conjunction with Gulf's participation in the American Petroleum Institute study conducted by the Memorial Sloan-Kettering Cancer Center (MSKCC). The results indicate no increased risk of brain tumor among workers at this Texas refinery.

Original languageEnglish (US)
Pages (from-to)130-138
Number of pages9
JournalAnnals of the New York Academy of Sciences
VolumeVol. 381
StatePublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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