A randomized trial of the impact of a programmable medication reminder device on quality of life in patients with AIDS

Albert W Wu, Claire Snyder, I. Chan Huang, Richard Skolasky, Henraya F. McGruder, Shivaun Celano, Ola A. Selnes, Adriana S. Andrade

Research output: Contribution to journalArticle

Abstract

This 6-month randomized controlled trial evaluated the impact on quality of life (QOL) of a medication reminder device for patients with HIV. Patients were eligible if they had taken three or fewer highly active antiretroviral therapy (HAART) regimens or were treatment naïve. The intervention group received the Disease Management Assistance System (DMAS), a prompting device that verbally reminds patients at medication times and electronically records doses, and a monthly 30 minute adherence educational session. Controls received education only. QOL was measured at baseline and 6 months using the Centers for Epidemiologic Studies Depression Scale (CES-D), Intrumental Activities of Daily Living (IADLs), and the Medical Outcomes Study HIV Health Survey (MOS-HIV). At baseline, 62 patients completed surveys (31 control, 31 DMAS); at month 6, 48 patients completed surveys (23 control, 25 DMAS). At month 6, controls had improved QOL scores for CES-D, IADLs, physical health, general health, pain, QOL, and role functioning, while participants in the DMAS arm had some deterioration in QOL scores. These differences persisted after controlling for demographics, baseline CD4, and adherence. DMAS was associated with improved adherence but decreased QOL.

Original languageEnglish (US)
Pages (from-to)773-781
Number of pages9
JournalAIDS Patient Care and STDs
Volume20
Issue number11
DOIs
StatePublished - Nov 2006

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Disease Management
Acquired Immunodeficiency Syndrome
Quality of Life
Equipment and Supplies
Activities of Daily Living
Epidemiologic Studies
HIV
Depression
Highly Active Antiretroviral Therapy
Health
Health Surveys
Randomized Controlled Trials
Demography
Outcome Assessment (Health Care)
Education
Pain
Surveys and Questionnaires
Therapeutics

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Leadership and Management
  • Nursing(all)

Cite this

A randomized trial of the impact of a programmable medication reminder device on quality of life in patients with AIDS. / Wu, Albert W; Snyder, Claire; Huang, I. Chan; Skolasky, Richard; McGruder, Henraya F.; Celano, Shivaun; Selnes, Ola A.; Andrade, Adriana S.

In: AIDS Patient Care and STDs, Vol. 20, No. 11, 11.2006, p. 773-781.

Research output: Contribution to journalArticle

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