A randomized controlled trial comparing the cuffed oropharyngeal airway and the laryngeal mask airway in spontaneously breathing anesthetized adults

Robert S Greenberg, Joseph Brimacombe, Alison Berry, Victoria Gouze, Steven Piantadosi, Elizabeth M. Dake

Research output: Contribution to journalArticle


Background: The cuffed oropharyngeal airway (COPA), a modified Guedel airway, was compared with the laryngeal mask airway (LMA) during spontaneous breathing anesthesia. Specifically examined were ease of use, physiologic tolerance, and the frequency of problems. Methods: Adult patients consented to random (2:1) assignment to either COPA (n = 302) or LMA (n = 151) for airway management during anesthesia with propofol, nitrous oxide, and oxygen. Results: Ease of insertion was similar, but the first-time successful insertion rate was higher with the LMA (COPA, 81% compared with LMA, 89%; P = 0.05). More brief manipulations (head tilt, chin lift, jaw thrust) were reported in the COPA group (average total number of manipulations: COPA, 1.1 ± 1.6 compared with LMA, 0.1 ± 0.2; P <0.001). Continuous airway support was used more frequently in the COPA group (COPA, 30% compared with LMA, 0%; P <0.0005). The incidences of aspiration, regurgitation, laryngospasm, wheezing, succinylcholine administration, oxygen saturation (Sp(O2))

Original languageEnglish (US)
Pages (from-to)970-977
Number of pages8
Issue number4
Publication statusPublished - 1998



  • Airway devices
  • Airway management
  • Complications
  • General anesthesia
  • Sore throat

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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