A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary artery disease

David L. Fischman, Martin B. Leon, Donald S. Baim, Richard A. Schatz, Michael P. Savage, Ian Penn, Katherine Detre, Lisa Veltri, Donald Ricci, Masakiyo Nobuyoshi, Michael Cleman, Richard Heuser, David Almond, Paul S. Teirstein, R. David Fish, Antonio Colombo, Jeffrey A Brinker, Jeffrey Moses, Alex Shaknovich, John HirshfeldStephen Bailey, Stephen Ellis, Randal Rake, Sheldon Goldberg

Research output: Contribution to journalArticle

Abstract

Background. Coronary-stent placement is a new technique in which a balloon-expandable, stainless-steel, slotted tube is implanted at the site of a coronary stenosis. The purpose of this study was to compare the effects of stent placement and standard balloon angioplasty on angiographically detected restenosis and clinical outcomes. Methods. We randomly assigned 410 patients with symptomatic coronary disease to elective placement of a Palmaz-Schatz stent or to standard balloon angioplasty. Coronary angiography was performed at base line, immediately after the procedure, and six months later. Results. The patients who underwent stenting had a higher rate of procedural success than those who underwent standard balloon angioplasty (96.1 percent vs. 89.6 percent, P = 0.011), a larger immediate increase in the diameter of the lumen (1.72±0.46 vs. 1.23±0.48 mm, P

Original languageEnglish (US)
Pages (from-to)496-501
Number of pages6
JournalNew England Journal of Medicine
Volume331
Issue number8
DOIs
StatePublished - Aug 25 1994

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Balloon Angioplasty
Stents
Coronary Artery Disease
Coronary Stenosis
Stainless Steel
Coronary Angiography
Coronary Disease
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Fischman, D. L., Leon, M. B., Baim, D. S., Schatz, R. A., Savage, M. P., Penn, I., ... Goldberg, S. (1994). A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary artery disease. New England Journal of Medicine, 331(8), 496-501. https://doi.org/10.1056/NEJM199408253310802

A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary artery disease. / Fischman, David L.; Leon, Martin B.; Baim, Donald S.; Schatz, Richard A.; Savage, Michael P.; Penn, Ian; Detre, Katherine; Veltri, Lisa; Ricci, Donald; Nobuyoshi, Masakiyo; Cleman, Michael; Heuser, Richard; Almond, David; Teirstein, Paul S.; Fish, R. David; Colombo, Antonio; Brinker, Jeffrey A; Moses, Jeffrey; Shaknovich, Alex; Hirshfeld, John; Bailey, Stephen; Ellis, Stephen; Rake, Randal; Goldberg, Sheldon.

In: New England Journal of Medicine, Vol. 331, No. 8, 25.08.1994, p. 496-501.

Research output: Contribution to journalArticle

Fischman, DL, Leon, MB, Baim, DS, Schatz, RA, Savage, MP, Penn, I, Detre, K, Veltri, L, Ricci, D, Nobuyoshi, M, Cleman, M, Heuser, R, Almond, D, Teirstein, PS, Fish, RD, Colombo, A, Brinker, JA, Moses, J, Shaknovich, A, Hirshfeld, J, Bailey, S, Ellis, S, Rake, R & Goldberg, S 1994, 'A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary artery disease', New England Journal of Medicine, vol. 331, no. 8, pp. 496-501. https://doi.org/10.1056/NEJM199408253310802
Fischman, David L. ; Leon, Martin B. ; Baim, Donald S. ; Schatz, Richard A. ; Savage, Michael P. ; Penn, Ian ; Detre, Katherine ; Veltri, Lisa ; Ricci, Donald ; Nobuyoshi, Masakiyo ; Cleman, Michael ; Heuser, Richard ; Almond, David ; Teirstein, Paul S. ; Fish, R. David ; Colombo, Antonio ; Brinker, Jeffrey A ; Moses, Jeffrey ; Shaknovich, Alex ; Hirshfeld, John ; Bailey, Stephen ; Ellis, Stephen ; Rake, Randal ; Goldberg, Sheldon. / A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary artery disease. In: New England Journal of Medicine. 1994 ; Vol. 331, No. 8. pp. 496-501.
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AU - Heuser, Richard

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AU - Moses, Jeffrey

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AU - Ellis, Stephen

AU - Rake, Randal

AU - Goldberg, Sheldon

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