A randomized clinical trial to reduce asthma morbidity among inner-city children: Results of the national cooperative inner-city asthma study

Richard Evans, Peter J. Gergen, Herman Mitchell, Meyer Kattan, Carolyn Kercsmar, Ellen Crain, John Anderson, Peyton Eggleston, Floyd J. Malveaux, H. James Wedner

Research output: Contribution to journalArticle

Abstract

Objective: To evaluate a family-focused asthma intervention designed for inner-city children 5 to 11 years old with moderate to severe asthma. Study design: Randomized, multisite, controlled trial to minimize symptom days (wheeze, loss of sleep, reduction in play activity) measured by a 2-week recall assessed at 2-month intervals over a 2-year follow-up period. The intervention was tailored to each family's individual asthma risk profile assessed at baseline. Results: Averaged over the first 12 months, participants in the intervention group (n = 515) reported 3.51 symptom days in the 2 weeks before each follow-up interview compared with 4.06 symptom days for the control group (n = 518), a difference of 0.55 (95% CI, 0.18 to 0.92, P = .004). The reduction among children with severe asthma was approximately 3 times greater (1.54 d/2 wk). More children in the control group (18.9%) were hospitalized during the intervention compared with children in the intervention group (14.8%), a decrease of 4.19% (CI, -8.75 to 0.36, P = .071). These improvements were maintained in the intervention group during the second year of follow-up, during which they did not have access to the asthma counselor. Conclusions: We demonstrated that an individually tailored, multifaceted intervention carried out by Masters-level social workers trained in asthma management can reduce asthma symptoms among children in the inner city.

Original languageEnglish (US)
Pages (from-to)332-338
Number of pages7
JournalJournal of Pediatrics
Volume135
Issue number3
DOIs
StatePublished - Jan 1 1999

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Evans, R., Gergen, P. J., Mitchell, H., Kattan, M., Kercsmar, C., Crain, E., Anderson, J., Eggleston, P., Malveaux, F. J., & Wedner, H. J. (1999). A randomized clinical trial to reduce asthma morbidity among inner-city children: Results of the national cooperative inner-city asthma study. Journal of Pediatrics, 135(3), 332-338. https://doi.org/10.1016/S0022-3476(99)70130-7