TY - JOUR
T1 - A Randomised Controlled Trial of Chewing Gum to Relieve Thirst in Chronic Heart Failure (RELIEVE-CHF)
AU - Allida, Sabine M.
AU - Shehab, Sajad
AU - Inglis, Sally C.
AU - Davidson, Patricia M.
AU - Hayward, Christopher S.
AU - Newton, Phillip J.
N1 - Funding Information:
Dr Sabine M Allida and Dr Sajad Shehab were funded by an Australian Postgraduate Award Scholarship by the Australian Government .
Funding Information:
Dr Sally C Inglis is currently supported by a Heart Foundation Future Leader Fellowship and was previously supported by a Cardiovascular Research Network Life Science Research Fellowship supported by the Heart Foundation and the NSW Office for Medical Research ( CR 11S 6226 ).
PY - 2020
Y1 - 2020
N2 - Background: Thirst is a common and troublesome symptom of patients with chronic heart failure (CHF). To date, there are no interventions to help alleviate thirst in this cohort. Chewing gum is a novel intervention, which has been tested in people undergoing haemodialysis, also prescribed with a fluid restricted therapy. The aim of this study was to determine the effect of chewing gum on the level of thirst in the short-term (average of 24 hours each day for 4 days) and in the longer-term (Days 7, 14 and 28) individuals with CHF. Methods: Seventy-one (71) individuals with CHF on oral loop diuretics were randomised to chewing gum (n=36) or control (n=35) for 2 weeks. Both groups were assessed for their level of thirst at Days 1–4, 7, 14 and 28. Results: Significant improvements in the level of thirst of those who received chewing gum compared to the control group at Day 4 (p=0.04) and Day 14 (p=0.02) were observed. Conclusion: Chewing gum provided relief from thirst in the short-term and in the longer term. This trial provides important information to inform future clinical trials on ways to relieve thirst.
AB - Background: Thirst is a common and troublesome symptom of patients with chronic heart failure (CHF). To date, there are no interventions to help alleviate thirst in this cohort. Chewing gum is a novel intervention, which has been tested in people undergoing haemodialysis, also prescribed with a fluid restricted therapy. The aim of this study was to determine the effect of chewing gum on the level of thirst in the short-term (average of 24 hours each day for 4 days) and in the longer-term (Days 7, 14 and 28) individuals with CHF. Methods: Seventy-one (71) individuals with CHF on oral loop diuretics were randomised to chewing gum (n=36) or control (n=35) for 2 weeks. Both groups were assessed for their level of thirst at Days 1–4, 7, 14 and 28. Results: Significant improvements in the level of thirst of those who received chewing gum compared to the control group at Day 4 (p=0.04) and Day 14 (p=0.02) were observed. Conclusion: Chewing gum provided relief from thirst in the short-term and in the longer term. This trial provides important information to inform future clinical trials on ways to relieve thirst.
KW - Chewing gum
KW - Chronic heart failure
KW - Randomised controlled trial
KW - Thirst
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U2 - 10.1016/j.hlc.2020.09.004
DO - 10.1016/j.hlc.2020.09.004
M3 - Article
C2 - 33032897
AN - SCOPUS:85092044798
JO - Heart Lung and Circulation
JF - Heart Lung and Circulation
SN - 1443-9506
ER -