TY - JOUR
T1 - A RandomisEd ControLled TrIal of ChEwing Gum to RelieVE Thirst in Chronic Heart Failure (RELIEVE-CHF)
AU - Allida, Sabine M.
AU - Shehab, Sajad
AU - Inglis, Sally C.
AU - Davidson, Patricia M.
AU - Hayward, Christopher S.
AU - Newton, Phillip J.
N1 - Funding Information:
Dr Sabine M Allida and Dr Sajad Shehab were funded by an Australian Postgraduate Award Scholarship by the Australian Government. Dr Sally C Inglis is currently supported by a Heart Foundation Future Leader Fellowship and was previously supported by a Cardiovascular Research Network Life Science Research Fellowship supported by the Heart Foundation and the NSW Office for Medical Research (CR 11S 6226). We would like to thank Ellen Montgomery and Julee McDonagh who provided assistance with recruiting participants in the trial. We would also like to thank Professor Lawrence Lam who provided statistical help.
Funding Information:
Dr Sabine M Allida and Dr Sajad Shehab were funded by an Australian Postgraduate Award Scholarship by the Australian Government .
Funding Information:
Dr Sally C Inglis is currently supported by a Heart Foundation Future Leader Fellowship and was previously supported by a Cardiovascular Research Network Life Science Research Fellowship supported by the Heart Foundation and the NSW Office for Medical Research ( CR 11S 6226 ).
Publisher Copyright:
© 2020 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ)
PY - 2021/4
Y1 - 2021/4
N2 - Background: Thirst is a common and troublesome symptom of patients with chronic heart failure (CHF). To date, there are no interventions to help alleviate thirst in this cohort. Chewing gum is a novel intervention, which has been tested in people undergoing haemodialysis, also prescribed with a fluid restricted therapy. The aim of this study was to determine the effect of chewing gum on the level of thirst in the short-term (average of 24 hours each day for 4 days) and in the longer-term (Days 7, 14 and 28) individuals with CHF. Methods: Seventy-one (71) individuals with CHF on oral loop diuretics were randomised to chewing gum (n=36) or control (n=35) for 2 weeks. Both groups were assessed for their level of thirst at Days 1–4, 7, 14 and 28. Results: Significant improvements in the level of thirst of those who received chewing gum compared to the control group at Day 4 (p=0.04) and Day 14 (p=0.02) were observed. Conclusion: Chewing gum provided relief from thirst in the short-term and in the longer term. This trial provides important information to inform future clinical trials on ways to relieve thirst.
AB - Background: Thirst is a common and troublesome symptom of patients with chronic heart failure (CHF). To date, there are no interventions to help alleviate thirst in this cohort. Chewing gum is a novel intervention, which has been tested in people undergoing haemodialysis, also prescribed with a fluid restricted therapy. The aim of this study was to determine the effect of chewing gum on the level of thirst in the short-term (average of 24 hours each day for 4 days) and in the longer-term (Days 7, 14 and 28) individuals with CHF. Methods: Seventy-one (71) individuals with CHF on oral loop diuretics were randomised to chewing gum (n=36) or control (n=35) for 2 weeks. Both groups were assessed for their level of thirst at Days 1–4, 7, 14 and 28. Results: Significant improvements in the level of thirst of those who received chewing gum compared to the control group at Day 4 (p=0.04) and Day 14 (p=0.02) were observed. Conclusion: Chewing gum provided relief from thirst in the short-term and in the longer term. This trial provides important information to inform future clinical trials on ways to relieve thirst.
KW - Chewing gum
KW - Chronic heart failure
KW - Randomised controlled trial
KW - Thirst
UR - http://www.scopus.com/inward/record.url?scp=85092044798&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85092044798&partnerID=8YFLogxK
U2 - 10.1016/j.hlc.2020.09.004
DO - 10.1016/j.hlc.2020.09.004
M3 - Article
C2 - 33032897
AN - SCOPUS:85092044798
VL - 30
SP - 516
EP - 524
JO - Heart Lung and Circulation
JF - Heart Lung and Circulation
SN - 1443-9506
IS - 4
ER -