A quick silver method for senile plaques and neurofibrillary tangles in paraffin sections

John C. Hedreen, Lisabeth S. Raskin, Donald L. Price

Research output: Contribution to journalArticlepeer-review

Abstract

A new silver method for senile plaques and neurofibrillary tangles (NFT) in paraffin sections is presented. This new technique is rapid in execution (15 min) and reveals senile plaques of all morphological types as well as NFT. The silver staining is spatially congruent with immunocytochemical staining for the β-amyloid peptide (Aβ) in adjacent sections.

Original languageEnglish (US)
Pages (from-to)279-284
Number of pages6
JournalBrain Research Bulletin
Volume35
Issue number3
DOIs
StatePublished - 1994

Keywords

  • Alzheimer's disease
  • Aβ peptide
  • Diagnosis of Alzheimer's disease
  • Neurofibrillary tangles
  • Senile plaques

ASJC Scopus subject areas

  • Neuroscience(all)

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