A quick silver method for senile plaques and neurofibrillary tangles in paraffin sections

John C. Hedreen; Lisabeth S. Raskin; Donald L. Price

doi:10.1016/0361-9230(94)90135-X

A quick silver method for senile plaques and neurofibrillary tangles in paraffin sections

John C. Hedreen, Lisabeth S. Raskin, Donald L. Price

School of Medicine

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A new silver method for senile plaques and neurofibrillary tangles (NFT) in paraffin sections is presented. This new technique is rapid in execution (15 min) and reveals senile plaques of all morphological types as well as NFT. The silver staining is spatially congruent with immunocytochemical staining for the β-amyloid peptide (Aβ) in adjacent sections.

Original language	English (US)
Pages (from-to)	279-284
Number of pages	6
Journal	Brain Research Bulletin
Volume	35
Issue number	3
DOIs	https://doi.org/10.1016/0361-9230(94)90135-X
State	Published - 1994

Keywords

Alzheimer's disease
Aβ peptide
Diagnosis of Alzheimer's disease
Neurofibrillary tangles
Senile plaques

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/0361-9230(94)90135-X

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title = "A quick silver method for senile plaques and neurofibrillary tangles in paraffin sections",

abstract = "A new silver method for senile plaques and neurofibrillary tangles (NFT) in paraffin sections is presented. This new technique is rapid in execution (15 min) and reveals senile plaques of all morphological types as well as NFT. The silver staining is spatially congruent with immunocytochemical staining for the β-amyloid peptide (Aβ) in adjacent sections.",

keywords = "Alzheimer's disease, Aβ peptide, Diagnosis of Alzheimer's disease, Neurofibrillary tangles, Senile plaques",

author = "Hedreen, {John C.} and Raskin, {Lisabeth S.} and Price, {Donald L.}",

year = "1994",

doi = "10.1016/0361-9230(94)90135-X",

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pages = "279--284",

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T1 - A quick silver method for senile plaques and neurofibrillary tangles in paraffin sections

AU - Hedreen, John C.

AU - Raskin, Lisabeth S.

AU - Price, Donald L.

PY - 1994

Y1 - 1994

N2 - A new silver method for senile plaques and neurofibrillary tangles (NFT) in paraffin sections is presented. This new technique is rapid in execution (15 min) and reveals senile plaques of all morphological types as well as NFT. The silver staining is spatially congruent with immunocytochemical staining for the β-amyloid peptide (Aβ) in adjacent sections.

AB - A new silver method for senile plaques and neurofibrillary tangles (NFT) in paraffin sections is presented. This new technique is rapid in execution (15 min) and reveals senile plaques of all morphological types as well as NFT. The silver staining is spatially congruent with immunocytochemical staining for the β-amyloid peptide (Aβ) in adjacent sections.

KW - Alzheimer's disease

KW - Aβ peptide

KW - Diagnosis of Alzheimer's disease

KW - Neurofibrillary tangles

KW - Senile plaques

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U2 - 10.1016/0361-9230(94)90135-X

DO - 10.1016/0361-9230(94)90135-X

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AN - SCOPUS:0028016508

SN - 0361-9230

VL - 35

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EP - 284

JO - Journal of Electrophysiological Techniques

JF - Journal of Electrophysiological Techniques

IS - 3

ER -

A quick silver method for senile plaques and neurofibrillary tangles in paraffin sections

Abstract

Keywords

ASJC Scopus subject areas

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