@inbook{1b3c7ea990f94840b3536d9e60714b6e,
title = "A quick look at slow saccades after cardiac surgery: where is the lesion?",
abstract = "Saccadic palsy is a reported complication of cardiac surgery. One case that came to autopsy showed midline pontine gliosis; however, in most cases, no lesions are evident on neuroimaging. Since the saccadic palsy may range from single large slow saccades to a {"}staircase{"} of very small saccades that are normal in speed, it seems plausible that more than one mechanism is possible. Here we postulate that, in those patients who make a staircase of small saccades, loss of cerebellar Purkinje cells could cause fastigial nucleus neurons to fire prematurely, thereby decelerating saccades via inhibitory burst neurons.",
keywords = "Purkinje cells, excitatory burst neuron, fastigial nucleus, inhibitory burst neuron, omnipause neurons, saccades, saccadic hypometria, saccadic palsy",
author = "David Solomon and Stefano Ramat and Leigh, {R. John} and David Zee",
note = "Funding Information: This work was supported by Christopher Cleveland Memorial Fund, NIH EY06717.",
year = "2008",
doi = "10.1016/S0079-6123(08)00685-7",
language = "English (US)",
isbn = "9780444531636",
series = "Progress in Brain Research",
publisher = "Elsevier",
pages = "587--590",
booktitle = "Using Eye Movements as an Experimental Probe of Brain function A Symposium in Honor of Jean Buttner-Ennever",
}