A quasi-local method for instantaneous frequency estimation with application to structural magnetic resonance images

Alvaro Ulloa, Paul Rodriguez, Jingyu Liu, Vince Calhoun, Marios Pattichis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Spatially-varying signal content can be effectively modeled using amplitude modulation-frequency modulation (AM-FM) representations. The AM-FM representation allow us to extract instantaneous amplitude (IA) and instantaneous frequency (IF) components that can be used to measure non-stationary content in biomedical images and videos. This paper introduces a new method for estimating the IA and the IF based on a quasi-local method (QLM). We provide an extensive comparison of AM-FM demodulation approaches based on QLM and a quasi-eigenfunction approximation method using three different filter-banks: (i) a separable, equiripple design, (ii) a Gabor filter bank, and (iii) a directional filter bank approach based on the Contourlet transform. The results document that the use of the new QLM method with an equiripple filter bank design gave the best IF magnitude estimates for a synthetic image. The new QLM method is then applied to a multi-site schizophrenia dataset (N=307). The dataset included structure magnetic resonance images from healthy controls and patients diagnosed with schizophrenia. The IF magnitude is shown to be less sensitive to variations across sites as opposed to the standard use of SMRI images that suffered from significant dependency on the scanner configurations on different collection sites. Furthermore, the regions of interest identified through the use of the IF magnitude are in agreement with previous studies.

Original languageEnglish (US)
Title of host publication2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1477-1480
Number of pages4
ISBN (Electronic)9781424479290
DOIs
StatePublished - Nov 2 2014
Externally publishedYes
Event2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, United States
Duration: Aug 26 2014Aug 30 2014

Publication series

Name2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014

Other

Other2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
CountryUnited States
CityChicago
Period8/26/148/30/14

ASJC Scopus subject areas

  • Health Informatics
  • Computer Science Applications
  • Biomedical Engineering
  • Medicine(all)

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