TY - GEN
T1 - A prototype detector for a novel high-resolution PET system
T2 - 2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record, NSS/MIC 2012
AU - Park, Ryeojin
AU - Miller, Brian W.
AU - Jha, Abhinav K.
AU - Furenlid, Lars R.
AU - Hunter, William C.J.
AU - Barrett, Harrison H.
PY - 2012
Y1 - 2012
N2 - We have designed and are developing a novel proof-of-concept PET system called BazookaPET. In order to complete the PET configuration, at least two detector elements are required to detect positron-electron annihilation events. Each detector element of the BazookaPET has two independent data acquisition channels. One side of the scintillation crystal is optically coupled to a 4×4 silicon photomultiplier (SiPM) array and the other side is a CCD-based gamma camera. Using these two separate channels, we can obtain data with high energy, temporal and spatial resolution data by associating the data outputs via several maximum-likelihood estimation (MLE) steps. In this work, we present the concept of the system and the prototype detector element. We focus on characterizing individual detector channels, and initial experimental calibration results are shown along with preliminary performance-evaluation results.We measured energy resolution and the integrated traces of the slit-beam images from both detector channel outputs. A photo-peak energy resolution of ∼5.3% FWHM was obtained from the SiPM and ∼48% FWHM from the CCD at 662 keV. We assumed SiPM signals follow Gaussian statistics and estimated the 2D interaction position using MLE. Based on our the calibration experiments, we computed the Cramér-Rao bound (CRB) for the SiPM detector channel and found that the CRB resolution is better than 1 mm in the center of the crystal.
AB - We have designed and are developing a novel proof-of-concept PET system called BazookaPET. In order to complete the PET configuration, at least two detector elements are required to detect positron-electron annihilation events. Each detector element of the BazookaPET has two independent data acquisition channels. One side of the scintillation crystal is optically coupled to a 4×4 silicon photomultiplier (SiPM) array and the other side is a CCD-based gamma camera. Using these two separate channels, we can obtain data with high energy, temporal and spatial resolution data by associating the data outputs via several maximum-likelihood estimation (MLE) steps. In this work, we present the concept of the system and the prototype detector element. We focus on characterizing individual detector channels, and initial experimental calibration results are shown along with preliminary performance-evaluation results.We measured energy resolution and the integrated traces of the slit-beam images from both detector channel outputs. A photo-peak energy resolution of ∼5.3% FWHM was obtained from the SiPM and ∼48% FWHM from the CCD at 662 keV. We assumed SiPM signals follow Gaussian statistics and estimated the 2D interaction position using MLE. Based on our the calibration experiments, we computed the Cramér-Rao bound (CRB) for the SiPM detector channel and found that the CRB resolution is better than 1 mm in the center of the crystal.
KW - CCD-based gamma camera
KW - PET imaging
KW - image intensifier
KW - molecular imaging
KW - monolithic LaBr:Ce
KW - silicon photomultiplier (SiPM)
UR - http://www.scopus.com/inward/record.url?scp=84881563128&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84881563128&partnerID=8YFLogxK
U2 - 10.1109/NSSMIC.2012.6551486
DO - 10.1109/NSSMIC.2012.6551486
M3 - Conference contribution
C2 - 26316682
AN - SCOPUS:84881563128
SN - 9781467320306
T3 - IEEE Nuclear Science Symposium Conference Record
SP - 2123
EP - 2127
BT - 2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record, NSS/MIC 2012
Y2 - 29 October 2012 through 3 November 2012
ER -