A prospective randomised comparative study on the influence of cydosporin and azathioprine on renal auograft survival and function

F. C. Henny; A. M. Kootte; J. H. Van Bockel; W. M. Baldwin; J. Hermans; B. Bos; L. A. Van Es; L. C. Paul

doi:10.1093/oxfordjournals.ndt.a091438

A prospective randomised comparative study on the influence of cydosporin and azathioprine on renal auograft survival and function

F. C. Henny, A. M. Kootte, J. H. Van Bockel, W. M. Baldwin, J. Hermans, B. Bos, L. A. Van Es, L. C. Paul

Research output: Contribution to journal › Article › peer-review

Abstract

To study the effectiveness and nephrotoxic sideeffects of cydosporin A (CsA) in renal transplant recipients, a prospective randomised trial was designed to compare CsA with azathioprine (Aza). Each treatment group consisted of 40 patients; in the CsA group, 18 were randomly selected for conversion to Aza after 3 months. The 1-year graft survival for CsA-treated patients was 87% compared with 66% for the Aza group (P=0.033). Anti-rejection therapy was administrated to 78% of the patients in the Aza group and 47% of those in the CsA group (P

Original language	English (US)
Pages (from-to)	44-49
Number of pages	6
Journal	Nephrology Dialysis Transplantation
Volume	1
Issue number	1
DOIs	https://doi.org/10.1093/oxfordjournals.ndt.a091438
State	Published - 1986
Externally published	Yes

Keywords

Cydosporin
Hypertension
Nephrotoxicity
Proteinuria
Renal transplantation

ASJC Scopus subject areas

Nephrology
Transplantation

Access to Document

10.1093/oxfordjournals.ndt.a091438

Cite this

A prospective randomised comparative study on the influence of cydosporin and azathioprine on renal auograft survival and function. / Henny, F. C.; Kootte, A. M.; Van Bockel, J. H.; Baldwin, W. M.; Hermans, J.; Bos, B.; Van Es, L. A.; Paul, L. C.

In: Nephrology Dialysis Transplantation, Vol. 1, No. 1, 1986, p. 44-49.

Research output: Contribution to journal › Article › peer-review

@article{a074baadfbea4c05b880ed0d84f3c156,

title = "A prospective randomised comparative study on the influence of cydosporin and azathioprine on renal auograft survival and function",

abstract = "To study the effectiveness and nephrotoxic sideeffects of cydosporin A (CsA) in renal transplant recipients, a prospective randomised trial was designed to compare CsA with azathioprine (Aza). Each treatment group consisted of 40 patients; in the CsA group, 18 were randomly selected for conversion to Aza after 3 months. The 1-year graft survival for CsA-treated patients was 87% compared with 66% for the Aza group (P=0.033). Anti-rejection therapy was administrated to 78% of the patients in the Aza group and 47% of those in the CsA group (P",

keywords = "Cydosporin, Hypertension, Nephrotoxicity, Proteinuria, Renal transplantation",

author = "Henny, {F. C.} and Kootte, {A. M.} and {Van Bockel}, {J. H.} and Baldwin, {W. M.} and J. Hermans and B. Bos and {Van Es}, {L. A.} and Paul, {L. C.}",

year = "1986",

doi = "10.1093/oxfordjournals.ndt.a091438",

language = "English (US)",

volume = "1",

pages = "44--49",

journal = "Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress",

issn = "0931-0509",

publisher = "Oxford University Press",

number = "1",

}

TY - JOUR

T1 - A prospective randomised comparative study on the influence of cydosporin and azathioprine on renal auograft survival and function

AU - Henny, F. C.

AU - Kootte, A. M.

AU - Van Bockel, J. H.

AU - Baldwin, W. M.

AU - Hermans, J.

AU - Bos, B.

AU - Van Es, L. A.

AU - Paul, L. C.

PY - 1986

Y1 - 1986

N2 - To study the effectiveness and nephrotoxic sideeffects of cydosporin A (CsA) in renal transplant recipients, a prospective randomised trial was designed to compare CsA with azathioprine (Aza). Each treatment group consisted of 40 patients; in the CsA group, 18 were randomly selected for conversion to Aza after 3 months. The 1-year graft survival for CsA-treated patients was 87% compared with 66% for the Aza group (P=0.033). Anti-rejection therapy was administrated to 78% of the patients in the Aza group and 47% of those in the CsA group (P

AB - To study the effectiveness and nephrotoxic sideeffects of cydosporin A (CsA) in renal transplant recipients, a prospective randomised trial was designed to compare CsA with azathioprine (Aza). Each treatment group consisted of 40 patients; in the CsA group, 18 were randomly selected for conversion to Aza after 3 months. The 1-year graft survival for CsA-treated patients was 87% compared with 66% for the Aza group (P=0.033). Anti-rejection therapy was administrated to 78% of the patients in the Aza group and 47% of those in the CsA group (P

KW - Cydosporin

KW - Hypertension

KW - Nephrotoxicity

KW - Proteinuria

KW - Renal transplantation

UR - http://www.scopus.com/inward/record.url?scp=0022824762&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022824762&partnerID=8YFLogxK

U2 - 10.1093/oxfordjournals.ndt.a091438

DO - 10.1093/oxfordjournals.ndt.a091438

M3 - Article

C2 - 3110662

AN - SCOPUS:0022824762

VL - 1

SP - 44

EP - 49

JO - Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress

JF - Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress

SN - 0931-0509

IS - 1

ER -

A prospective randomised comparative study on the influence of cydosporin and azathioprine on renal auograft survival and function

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this