A prospective multicenter study on laparoscopic treatment of gastroesophageal reflux disease in Italy: Type of surgery, conversions, complications, and early results

G. Zaninotto, D. Molena, E. Ancona, A. Peracchia, L. Bonavina, M. Costantini, L. Nicoletti, F. Favretti, S. Valletta, C. Sartori, B. Franzato, G. B. Antonello, G. Di Falco, M. Pavanello, M. Morino, F. Rebecchi, G. Melotti, A. Lanzani, G. Viola, E. ProcacciniR. Ruggiero, N. Basso, A. Genco, S. Rea, E. Croce, S. Olmi, U. Parini, A. Fosson, E. Lale Murix, A. Del Genio, V. Landolfi, R. Rosati, U. Fumagalli, S. Bona, F. Bresadola, V. Bresadola, G. Terrosu, D. Corso, M. De Bernardinis, F. Basile, M. Migliore, R. Vecchioni, M. Saviano, A. Picciocchi, R. Coppola, G. Castrucci, G. C. Botta, S. Contini, M. Rossi, M. Anselmino

Research output: Contribution to journalArticle


Background: A national survey was undertaken by the Italian Society for Laparoscopic Surgery to investigate the prevalence, indications, conversion rate, mortality, morbidity, and early results of laparoscopic antireflux surgery. Methods: Beginning on January 1, 1996, all of the centers taking part in this study were asked to complete a questionnaire on each patient. The questionnaire was divided into four parts and covered such areas as indications for surgery and preoperative workup, type of operation performed and certain aspects of the surgical technique, conversions and their causes, intraoperative and postoperative complications (within 4 weeks), and details of the postoperative course. The last part of the questionnaire focused on the follow-up period and was designed to gather data on recurrence of preoperative symptoms, postoperative symptoms (dysphagia, gas bloat), and postoperative test findings. Results: As of June 30 1998, 21 centers were taking part in the study and 621 patients were enrolled, with a median of 27 patients per center (less than one patient/month). The most popular technique was the Nissen-Rossetti (52%), followed by the Nissen (33%) and Toupet procedures (13%). Other techniques, such as the Dor and Lortat-Jacob, were used in the remainder of cases. Patients who received a Toupet procedure had a higher incidence of defective peristalsis (p <0.05). The conversion rate to open surgery was 2.9%. The most common causes of conversion were inability to reduce the hiatus hernia or distal esophagus in the abdomen and adhesions from previous surgery. Perforation of the stomach and esophagus occurred in 90% of patients. Despite these favorable results, however, this type of surgery is not yet as widely employed in Italy as in other countries.

Original languageEnglish (US)
Pages (from-to)282-288
Number of pages7
JournalSurgical Endoscopy and Other Interventional Techniques
Issue number3
StatePublished - Mar 2000
Externally publishedYes



  • Fundoplication
  • Gastroesophageal reflux disease
  • Laparoscopic antireflux surgery

ASJC Scopus subject areas

  • Surgery

Cite this

Zaninotto, G., Molena, D., Ancona, E., Peracchia, A., Bonavina, L., Costantini, M., Nicoletti, L., Favretti, F., Valletta, S., Sartori, C., Franzato, B., Antonello, G. B., Di Falco, G., Pavanello, M., Morino, M., Rebecchi, F., Melotti, G., Lanzani, A., Viola, G., ... Anselmino, M. (2000). A prospective multicenter study on laparoscopic treatment of gastroesophageal reflux disease in Italy: Type of surgery, conversions, complications, and early results. Surgical Endoscopy and Other Interventional Techniques, 14(3), 282-288. https://doi.org/10.1007/s004640000043