A Prospective, Multicenter Study of the AIMS65 Score Compared with the Glasgow-Blatchford Score in Predicting Upper Gastrointestinal Hemorrhage Outcomes

Marwan S. Abougergi, Joseph P. Charpentier, Emily Bethea, Abbas Rupawala, Joan Kheder, Dominic Nompleggi, Peter Liang, Anne C. Travis, John R. Saltzman

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The AIMS65 score and the Glasgow-Blatchford risk score (GBRS) are validated preendoscopic risk scores for upper gastrointestinal hemorrhage (UGIH). Goals: To compare the 2 scores' performance in predicting important outcomes in UGIH. Study: A prospective cohort study in 2 tertiary referral centers and 1 community teaching hospital. Adults with UGIH were included. The AIMS65 score and GBRS were calculated for each patient. The primary outcome was inpatient mortality. Secondary outcomes were 30-day mortality, in-hospital rebleeding, 30-day rebleeding, length of stay, and a composite endpoint of in-hospital mortality, transfusions, or need for intervention (endoscopic, radiologic, or surgical treatment). The area under the receiver operating characteristic curve (AUROC) was calculated for each score and outcome. Results: A total of 298 patients were enrolled. The AIMS65 score was superior to the GBRS in predicting in-hospital mortality (AUROC, 0.85 vs. 0.66; P

Original languageEnglish (US)
Pages (from-to)464-469
Number of pages6
JournalJournal of Clinical Gastroenterology
Volume50
Issue number6
DOIs
StatePublished - 2016
Externally publishedYes

Keywords

  • mortality
  • prognosis
  • severity of illness index
  • upper gastrointestinal hemorrhage

ASJC Scopus subject areas

  • Gastroenterology

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