A prospective, contralateral comparison of photorefractive keratectomy (PRK) versus thin-flap LASIK: Assessment of visual function

Bryndon B. Hatch, Majid Moshirfar, Andrew J. Ollerton, Shameema Sikder, Mark D. Mifflin

Research output: Contribution to journalArticle

Abstract

Purpose: To compare differences in visual acuity, contrast sensitivity, complications, and higher-order ocular aberrations (HOAs) in eyes with stable myopia undergoing either photorefractive keratectomy (PRK) or thin-flap laser in situ keratomileusis (LASIK) (intended flap thickness of 90 μm) using the VISX Star S4 CustomVue excimer laser and the IntraLase FS60 femtosecond laser at 1, 3, and 6 months postoperatively. Methods: In this prospective, masked, and randomized pilot study, refractive surgery was performed contralaterally on 52 eyes: 26 with PRK and 26 with thin-flap LASIK. Primary outcome measures were uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), contrast sensitivity, and complications. Results: At 6 months, mean values for UDVA (logMAR) were -0.043 ± 0.668 and -0.061 ± 0.099 in the PRK and thin-flap LASIK groups, respectively (n = 25, P = 0.466). UDVA of 20/20 or better was achieved in 96% of eyes undergoing PRK and 92% of eyes undergoing thin-flap LASIK, whereas 20/15 vision or better was achieved in 73% of eyes undergoing PRK and 72% of eyes undergoing thin-flap LASIK (P> 0.600). Significant differences were not found between treatment groups in contrast sensitivity (P ≥ 0.156) or CDVA (P = 0.800) at postoperative 6 months. Types of complications differed between groups, notably 35% of eyes in the thin-flap LASIK group experiencing complications, including microstriae and 2 flap tears. Conclusion: Under well-controlled surgical conditions, PRK and thin-flap LASIK refractive surgeries achieve similar results in visual acuity, contrast sensitivity, and induction of HOAs, with differences in experienced complications.

Original languageEnglish (US)
Pages (from-to)451-457
Number of pages7
JournalClinical Ophthalmology
Volume5
Issue number1
DOIs
StatePublished - 2011

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Photorefractive Keratectomy
Laser In Situ Keratomileusis
Visual Acuity
Contrast Sensitivity
Refractive Surgical Procedures
Excimer Lasers
Myopia
Lasers
Outcome Assessment (Health Care)

Keywords

  • Photorefractive keratectomy
  • Thin-flap LASIK
  • Visual function

ASJC Scopus subject areas

  • Ophthalmology

Cite this

A prospective, contralateral comparison of photorefractive keratectomy (PRK) versus thin-flap LASIK : Assessment of visual function. / Hatch, Bryndon B.; Moshirfar, Majid; Ollerton, Andrew J.; Sikder, Shameema; Mifflin, Mark D.

In: Clinical Ophthalmology, Vol. 5, No. 1, 2011, p. 451-457.

Research output: Contribution to journalArticle

Hatch, Bryndon B. ; Moshirfar, Majid ; Ollerton, Andrew J. ; Sikder, Shameema ; Mifflin, Mark D. / A prospective, contralateral comparison of photorefractive keratectomy (PRK) versus thin-flap LASIK : Assessment of visual function. In: Clinical Ophthalmology. 2011 ; Vol. 5, No. 1. pp. 451-457.
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abstract = "Purpose: To compare differences in visual acuity, contrast sensitivity, complications, and higher-order ocular aberrations (HOAs) in eyes with stable myopia undergoing either photorefractive keratectomy (PRK) or thin-flap laser in situ keratomileusis (LASIK) (intended flap thickness of 90 μm) using the VISX Star S4 CustomVue excimer laser and the IntraLase FS60 femtosecond laser at 1, 3, and 6 months postoperatively. Methods: In this prospective, masked, and randomized pilot study, refractive surgery was performed contralaterally on 52 eyes: 26 with PRK and 26 with thin-flap LASIK. Primary outcome measures were uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), contrast sensitivity, and complications. Results: At 6 months, mean values for UDVA (logMAR) were -0.043 ± 0.668 and -0.061 ± 0.099 in the PRK and thin-flap LASIK groups, respectively (n = 25, P = 0.466). UDVA of 20/20 or better was achieved in 96{\%} of eyes undergoing PRK and 92{\%} of eyes undergoing thin-flap LASIK, whereas 20/15 vision or better was achieved in 73{\%} of eyes undergoing PRK and 72{\%} of eyes undergoing thin-flap LASIK (P> 0.600). Significant differences were not found between treatment groups in contrast sensitivity (P ≥ 0.156) or CDVA (P = 0.800) at postoperative 6 months. Types of complications differed between groups, notably 35{\%} of eyes in the thin-flap LASIK group experiencing complications, including microstriae and 2 flap tears. Conclusion: Under well-controlled surgical conditions, PRK and thin-flap LASIK refractive surgeries achieve similar results in visual acuity, contrast sensitivity, and induction of HOAs, with differences in experienced complications.",
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T1 - A prospective, contralateral comparison of photorefractive keratectomy (PRK) versus thin-flap LASIK

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AU - Hatch, Bryndon B.

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AU - Sikder, Shameema

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AB - Purpose: To compare differences in visual acuity, contrast sensitivity, complications, and higher-order ocular aberrations (HOAs) in eyes with stable myopia undergoing either photorefractive keratectomy (PRK) or thin-flap laser in situ keratomileusis (LASIK) (intended flap thickness of 90 μm) using the VISX Star S4 CustomVue excimer laser and the IntraLase FS60 femtosecond laser at 1, 3, and 6 months postoperatively. Methods: In this prospective, masked, and randomized pilot study, refractive surgery was performed contralaterally on 52 eyes: 26 with PRK and 26 with thin-flap LASIK. Primary outcome measures were uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), contrast sensitivity, and complications. Results: At 6 months, mean values for UDVA (logMAR) were -0.043 ± 0.668 and -0.061 ± 0.099 in the PRK and thin-flap LASIK groups, respectively (n = 25, P = 0.466). UDVA of 20/20 or better was achieved in 96% of eyes undergoing PRK and 92% of eyes undergoing thin-flap LASIK, whereas 20/15 vision or better was achieved in 73% of eyes undergoing PRK and 72% of eyes undergoing thin-flap LASIK (P> 0.600). Significant differences were not found between treatment groups in contrast sensitivity (P ≥ 0.156) or CDVA (P = 0.800) at postoperative 6 months. Types of complications differed between groups, notably 35% of eyes in the thin-flap LASIK group experiencing complications, including microstriae and 2 flap tears. Conclusion: Under well-controlled surgical conditions, PRK and thin-flap LASIK refractive surgeries achieve similar results in visual acuity, contrast sensitivity, and induction of HOAs, with differences in experienced complications.

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