A PDZ protein ushers in new links

C. Montell

doi:10.1038/79186

A PDZ protein ushers in new links

C. Montell

School of Medicine

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Usher syndrome is a major cause of combined deafness and blindness. One form of the disease, termed USH1C, is now found to be caused by mutations in the gene encoding a PDZ-containing protein, harmonin. As interactions between PDZ proteins and their targets are known to mediate protein localization, signalling and maintenance of membrane characteristics, this discovery should accelerate our understanding of Usher syndrome and other auditory disorders.

Original language	English (US)
Pages (from-to)	6-7
Number of pages	2
Journal	Nature Genetics
Volume	26
Issue number	1
DOIs	https://doi.org/10.1038/79186
State	Published - 2000

ASJC Scopus subject areas

Genetics(clinical)
Genetics

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10.1038/79186

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A PDZ protein ushers in new links

Abstract

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