A one‐dimensional velocity technique for NMR measurement of aortic distensibility

Christopher J. Hardy, Bradley D. Bolster, Elliot R. McVeigh, William J. Adams, Elias A. Zerhouni

Research output: Contribution to journalArticlepeer-review

Abstract

A technique is presented for rapidly and noninvasively determining aortic distensibility, by NMR measurement of wave velocity in the aorta. A two–dimensional NMR selective‐excitation pulse is used to repeatedly excite a cylinder of magnetization in the aorta, with magnetization read out along the cylinder axis each time. A toggled bipolar flow‐encoding pulse is applied prior to readout, to produce a one‐dimensional phase‐contrast flow image. Cardiac gating and data interleaving are employed to improve the effective time resolution to 2 ms. Wave velocities are determined from the slope of the leading edge of flow measured on the resulting M‐mode velocity image. The technique is sensitive over a range of distensibilities from 10−8 to 10−3 m s2/kg. The average value in the descending thoracic aorta in seven normal subjects was found to be 4.8 × 10−5 m s2/kg, with a significant inverse correlation with age.

Original languageEnglish (US)
Pages (from-to)513-520
Number of pages8
JournalMagnetic resonance in medicine
Volume31
Issue number5
DOIs
StatePublished - May 1994

Keywords

  • aortic distensibility
  • blood velocity
  • compliance
  • wave speed

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'A one‐dimensional velocity technique for NMR measurement of aortic distensibility'. Together they form a unique fingerprint.

Cite this