A one-dimensional velocity technique for NMR measurement of aortic distensibility

C. J. Hardy, B. D. Bolster, E. R. McVeigh, W. J. Adams, Elias Zerhouni

Research output: Contribution to journalArticle

Abstract

A technique is presented for rapidly and noninvasively determining aortic distensibility, by NMR measurement of wave velocity in the aorta. A two- dimensional NMR selective-excitation pulse is used to repeatedly excite a cylinder of magnetization in the aorta, with magnetization read out along the cylinder axis each time. A toggled bipolar flow-encoding pulse is applied prior to readout, to produce a one-dimensional phase-contrast flow image. Cardiac gating and data interleaving are employed to improve the effective time resolution to 2 ms. Wave velocities are determined from the slope of the leading edge of flow measured on the resulting M-mode velocity image. The technique is sensitive over a range of distensibilities from 10-6 to 10- 3 m s2/kg. The average value in the descending thoracic aorta in seven normal subjects was found to be 4.8 x 10-5 m s2/kg, with a significant inverse correlation with age.

Original languageEnglish (US)
Pages (from-to)513-520
Number of pages8
JournalMagnetic Resonance in Medicine
Volume31
Issue number5
StatePublished - 1994

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Thoracic Aorta
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Aorta

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Hardy, C. J., Bolster, B. D., McVeigh, E. R., Adams, W. J., & Zerhouni, E. (1994). A one-dimensional velocity technique for NMR measurement of aortic distensibility. Magnetic Resonance in Medicine, 31(5), 513-520.

A one-dimensional velocity technique for NMR measurement of aortic distensibility. / Hardy, C. J.; Bolster, B. D.; McVeigh, E. R.; Adams, W. J.; Zerhouni, Elias.

In: Magnetic Resonance in Medicine, Vol. 31, No. 5, 1994, p. 513-520.

Research output: Contribution to journalArticle

Hardy, CJ, Bolster, BD, McVeigh, ER, Adams, WJ & Zerhouni, E 1994, 'A one-dimensional velocity technique for NMR measurement of aortic distensibility', Magnetic Resonance in Medicine, vol. 31, no. 5, pp. 513-520.
Hardy, C. J. ; Bolster, B. D. ; McVeigh, E. R. ; Adams, W. J. ; Zerhouni, Elias. / A one-dimensional velocity technique for NMR measurement of aortic distensibility. In: Magnetic Resonance in Medicine. 1994 ; Vol. 31, No. 5. pp. 513-520.
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