A nuclear radiation detector system with integrated readout for SPECT/MR small animal imaging

Suleyman Azman, Jon Gjærum, Dirk Meier, L. Tugan Muftuler, Gunnar Mæhlum, Orhan Nalcioglu, Bradley E. Patt, Bjørn Sundal, Marek Szawlowski, Benjamin M.W. Tsui, Douglas J. Wagenaar, Yuchuang Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have developed and constructed an MR-compatible single photon emission computed tomography (SPECT) system for small animal molecular imaging applications. The system consists of identical radiation imaging modules and a multi-pinhole collimator sleeve. The modular design results in a very compact system which allows for easy insertion into state-of-the-art small animal MRI systems. This development leads to a multi-modality system that allows one to accurately coregister SPECT and MR images in space and time. The MR-compatible SPECT unit has a barrel shape with 119-mm outer diameter designed to fit into an MRI system with a 120-mm diameter inner bore. The inner diameter of the SPECT unit is 35 mm which is large enough to fit a mouse, and provides a 30-mm diameter imaging field of view (FOV). The system does not require active cooling due to its low-power dissipation. The radiation sensor performance is not affected by the presence of the magnetic field from the MRI system. The results are very promising for applications of the SPECT/MR system to small animal imaging.

Original languageEnglish (US)
Title of host publication2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
Pages2311-2317
Number of pages7
DOIs
StatePublished - Dec 1 2007
Event2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC - Honolulu, HI, United States
Duration: Oct 27 2007Nov 3 2007

Publication series

NameIEEE Nuclear Science Symposium Conference Record
Volume3
ISSN (Print)1095-7863

Other

Other2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
CountryUnited States
CityHonolulu, HI
Period10/27/0711/3/07

Keywords

  • CZT
  • Cadmium zinc telluride
  • CdZnTe
  • Magnetic resonance (MR)
  • Molecular imaging
  • Multi-modality imaging
  • Radiation imaging module
  • Single photon emission computed tomography (SPECT)

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Azman, S., Gjærum, J., Meier, D., Muftuler, L. T., Mæhlum, G., Nalcioglu, O., Patt, B. E., Sundal, B., Szawlowski, M., Tsui, B. M. W., Wagenaar, D. J., & Wang, Y. (2007). A nuclear radiation detector system with integrated readout for SPECT/MR small animal imaging. In 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC (pp. 2311-2317). [4436608] (IEEE Nuclear Science Symposium Conference Record; Vol. 3). https://doi.org/10.1109/NSSMIC.2007.4436608