A nuclear radiation detector system with integrated readout for SPECT/MR small animal imaging

Suleyman Azman; Jon Gjærum; Dirk Meier; L. Tugan Muftuler; Gunnar Mæhlum; Orhan Nalcioglu; Bradley E. Patt; Bjørn Sundal; Marek Szawlowski; Benjamin M.W. Tsui; Douglas J. Wagenaar; Yuchuang Wang

doi:10.1109/NSSMIC.2007.4436608

A nuclear radiation detector system with integrated readout for SPECT/MR small animal imaging

Suleyman Azman, Jon Gjærum, Dirk Meier, L. Tugan Muftuler, Gunnar Mæhlum, Orhan Nalcioglu, Bradley E. Patt, Bjørn Sundal, Marek Szawlowski, Benjamin M.W. Tsui, Douglas J. Wagenaar, Yuchuang Wang

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

14 Scopus citations

Abstract

We have developed and constructed an MR-compatible single photon emission computed tomography (SPECT) system for small animal molecular imaging applications. The system consists of identical radiation imaging modules and a multi-pinhole collimator sleeve. The modular design results in a very compact system which allows for easy insertion into state-of-the-art small animal MRI systems. This development leads to a multi-modality system that allows one to accurately coregister SPECT and MR images in space and time. The MR-compatible SPECT unit has a barrel shape with 119-mm outer diameter designed to fit into an MRI system with a 120-mm diameter inner bore. The inner diameter of the SPECT unit is 35 mm which is large enough to fit a mouse, and provides a 30-mm diameter imaging field of view (FOV). The system does not require active cooling due to its low-power dissipation. The radiation sensor performance is not affected by the presence of the magnetic field from the MRI system. The results are very promising for applications of the SPECT/MR system to small animal imaging.

Original language	English (US)
Title of host publication	2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
Pages	2311-2317
Number of pages	7
DOIs	https://doi.org/10.1109/NSSMIC.2007.4436608
State	Published - 2007
Event	2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC - Honolulu, HI, United States Duration: Oct 27 2007 → Nov 3 2007

Publication series

Name	IEEE Nuclear Science Symposium Conference Record
Volume	3
ISSN (Print)	1095-7863

Other

Other	2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC
Country/Territory	United States
City	Honolulu, HI
Period	10/27/07 → 11/3/07

Keywords

CZT
Cadmium zinc telluride
CdZnTe
Magnetic resonance (MR)
Molecular imaging
Multi-modality imaging
Radiation imaging module
Single photon emission computed tomography (SPECT)

ASJC Scopus subject areas

Radiation
Nuclear and High Energy Physics
Radiology Nuclear Medicine and imaging

Access to Document

10.1109/NSSMIC.2007.4436608

Cite this

Azman, S., Gjærum, J., Meier, D., Muftuler, L. T., Mæhlum, G., Nalcioglu, O., Patt, B. E., Sundal, B., Szawlowski, M., Tsui, B. M. W., Wagenaar, D. J., & Wang, Y. (2007). A nuclear radiation detector system with integrated readout for SPECT/MR small animal imaging. In 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC (pp. 2311-2317). Article 4436608 (IEEE Nuclear Science Symposium Conference Record; Vol. 3). https://doi.org/10.1109/NSSMIC.2007.4436608

A nuclear radiation detector system with integrated readout for SPECT/MR small animal imaging. / Azman, Suleyman; Gjærum, Jon; Meier, Dirk et al.
2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC. 2007. p. 2311-2317 4436608 (IEEE Nuclear Science Symposium Conference Record; Vol. 3).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Azman, S, Gjærum, J, Meier, D, Muftuler, LT, Mæhlum, G, Nalcioglu, O, Patt, BE, Sundal, B, Szawlowski, M, Tsui, BMW, Wagenaar, DJ & Wang, Y 2007, A nuclear radiation detector system with integrated readout for SPECT/MR small animal imaging. in 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC., 4436608, IEEE Nuclear Science Symposium Conference Record, vol. 3, pp. 2311-2317, 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC, Honolulu, HI, United States, 10/27/07. https://doi.org/10.1109/NSSMIC.2007.4436608

@inproceedings{a8767e715ac04c49afe47be0e92c2b4d,

title = "A nuclear radiation detector system with integrated readout for SPECT/MR small animal imaging",

abstract = "We have developed and constructed an MR-compatible single photon emission computed tomography (SPECT) system for small animal molecular imaging applications. The system consists of identical radiation imaging modules and a multi-pinhole collimator sleeve. The modular design results in a very compact system which allows for easy insertion into state-of-the-art small animal MRI systems. This development leads to a multi-modality system that allows one to accurately coregister SPECT and MR images in space and time. The MR-compatible SPECT unit has a barrel shape with 119-mm outer diameter designed to fit into an MRI system with a 120-mm diameter inner bore. The inner diameter of the SPECT unit is 35 mm which is large enough to fit a mouse, and provides a 30-mm diameter imaging field of view (FOV). The system does not require active cooling due to its low-power dissipation. The radiation sensor performance is not affected by the presence of the magnetic field from the MRI system. The results are very promising for applications of the SPECT/MR system to small animal imaging.",

keywords = "CZT, Cadmium zinc telluride, CdZnTe, Magnetic resonance (MR), Molecular imaging, Multi-modality imaging, Radiation imaging module, Single photon emission computed tomography (SPECT)",

author = "Suleyman Azman and Jon Gj{\ae}rum and Dirk Meier and Muftuler, {L. Tugan} and Gunnar M{\ae}hlum and Orhan Nalcioglu and Patt, {Bradley E.} and Bj{\o}rn Sundal and Marek Szawlowski and Tsui, {Benjamin M.W.} and Wagenaar, {Douglas J.} and Yuchuang Wang",

year = "2007",

doi = "10.1109/NSSMIC.2007.4436608",

language = "English (US)",

isbn = "1424409233",

series = "IEEE Nuclear Science Symposium Conference Record",

pages = "2311--2317",

booktitle = "2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC",

note = "2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC ; Conference date: 27-10-2007 Through 03-11-2007",

}

TY - GEN

T1 - A nuclear radiation detector system with integrated readout for SPECT/MR small animal imaging

AU - Azman, Suleyman

AU - Gjærum, Jon

AU - Meier, Dirk

AU - Muftuler, L. Tugan

AU - Mæhlum, Gunnar

AU - Nalcioglu, Orhan

AU - Patt, Bradley E.

AU - Sundal, Bjørn

AU - Szawlowski, Marek

AU - Tsui, Benjamin M.W.

AU - Wagenaar, Douglas J.

AU - Wang, Yuchuang

PY - 2007

Y1 - 2007

N2 - We have developed and constructed an MR-compatible single photon emission computed tomography (SPECT) system for small animal molecular imaging applications. The system consists of identical radiation imaging modules and a multi-pinhole collimator sleeve. The modular design results in a very compact system which allows for easy insertion into state-of-the-art small animal MRI systems. This development leads to a multi-modality system that allows one to accurately coregister SPECT and MR images in space and time. The MR-compatible SPECT unit has a barrel shape with 119-mm outer diameter designed to fit into an MRI system with a 120-mm diameter inner bore. The inner diameter of the SPECT unit is 35 mm which is large enough to fit a mouse, and provides a 30-mm diameter imaging field of view (FOV). The system does not require active cooling due to its low-power dissipation. The radiation sensor performance is not affected by the presence of the magnetic field from the MRI system. The results are very promising for applications of the SPECT/MR system to small animal imaging.

AB - We have developed and constructed an MR-compatible single photon emission computed tomography (SPECT) system for small animal molecular imaging applications. The system consists of identical radiation imaging modules and a multi-pinhole collimator sleeve. The modular design results in a very compact system which allows for easy insertion into state-of-the-art small animal MRI systems. This development leads to a multi-modality system that allows one to accurately coregister SPECT and MR images in space and time. The MR-compatible SPECT unit has a barrel shape with 119-mm outer diameter designed to fit into an MRI system with a 120-mm diameter inner bore. The inner diameter of the SPECT unit is 35 mm which is large enough to fit a mouse, and provides a 30-mm diameter imaging field of view (FOV). The system does not require active cooling due to its low-power dissipation. The radiation sensor performance is not affected by the presence of the magnetic field from the MRI system. The results are very promising for applications of the SPECT/MR system to small animal imaging.

KW - CZT

KW - Cadmium zinc telluride

KW - CdZnTe

KW - Magnetic resonance (MR)

KW - Molecular imaging

KW - Multi-modality imaging

KW - Radiation imaging module

KW - Single photon emission computed tomography (SPECT)

UR - http://www.scopus.com/inward/record.url?scp=48349122218&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=48349122218&partnerID=8YFLogxK

U2 - 10.1109/NSSMIC.2007.4436608

DO - 10.1109/NSSMIC.2007.4436608

M3 - Conference contribution

AN - SCOPUS:48349122218

SN - 1424409233

SN - 9781424409235

T3 - IEEE Nuclear Science Symposium Conference Record

SP - 2311

EP - 2317

BT - 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC

T2 - 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS-MIC

Y2 - 27 October 2007 through 3 November 2007

ER -

A nuclear radiation detector system with integrated readout for SPECT/MR small animal imaging

Abstract

Publication series

Other

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this