A novel wavelet based algorithm for spike and wave detection in absence epilepsy

Petros Xanthopoulos, Steffen Rebennack, Chang Chia Liu, Jicong Zhang, Gregory L. Holmes, Basim M. Uthman, Panos M. Pardalos

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Absence seizures are characterized by sudden loss of consciousness and interruption of ongoing motor activities for a brief period of time lasting few to several seconds and up to half a minute. Due to their brevity and subtle clinical manifestations absence seizures are easily missed by inexperienced observers. Accurate evaluation of their high frequency of recurrence can be a challenge even for experienced observers. We present a novel method for detecting and analyzing absence seizures acquired from electroencephalogram (EEG) recordings in patients with absence seizures. Six patients were included in this study; two seizure free, of a total recording time of 26 hours, and four experiencing over 100 seizures within 14.5 hours of total recordings. Our algorithm detected only one false positive finding in the first seizure free patients and 148 of 186 continuous uninterrupted 3Hz spike and wave discharge (SWD) epochs in the rest of the patients. Out of the total 38 missed SWD epochs 28 were <2.1 sec in duration. The remaining epochs included interrupted 3Hz SWDs. Our proposed algorithm offers an efficient automatic detection scheme that can be used in diagnostic and therapeutic evaluations in patients with absence seizures.

Original languageEnglish (US)
Title of host publication10th IEEE International Conference on Bioinformatics and Bioengineering 2010, BIBE 2010
Pages14-19
Number of pages6
DOIs
StatePublished - 2010
Externally publishedYes
Event10th IEEE International Conference on Bioinformatics and Bioengineering, BIBE-2010 - Philadelphia, PA, United States
Duration: May 31 2010Jun 3 2010

Other

Other10th IEEE International Conference on Bioinformatics and Bioengineering, BIBE-2010
CountryUnited States
CityPhiladelphia, PA
Period5/31/106/3/10

Fingerprint

Absence Epilepsy
Electroencephalography
Seizures
Unconsciousness
Motor Activity
Recurrence

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics

Cite this

Xanthopoulos, P., Rebennack, S., Liu, C. C., Zhang, J., Holmes, G. L., Uthman, B. M., & Pardalos, P. M. (2010). A novel wavelet based algorithm for spike and wave detection in absence epilepsy. In 10th IEEE International Conference on Bioinformatics and Bioengineering 2010, BIBE 2010 (pp. 14-19). [5521720] https://doi.org/10.1109/BIBE.2010.12

A novel wavelet based algorithm for spike and wave detection in absence epilepsy. / Xanthopoulos, Petros; Rebennack, Steffen; Liu, Chang Chia; Zhang, Jicong; Holmes, Gregory L.; Uthman, Basim M.; Pardalos, Panos M.

10th IEEE International Conference on Bioinformatics and Bioengineering 2010, BIBE 2010. 2010. p. 14-19 5521720.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Xanthopoulos, P, Rebennack, S, Liu, CC, Zhang, J, Holmes, GL, Uthman, BM & Pardalos, PM 2010, A novel wavelet based algorithm for spike and wave detection in absence epilepsy. in 10th IEEE International Conference on Bioinformatics and Bioengineering 2010, BIBE 2010., 5521720, pp. 14-19, 10th IEEE International Conference on Bioinformatics and Bioengineering, BIBE-2010, Philadelphia, PA, United States, 5/31/10. https://doi.org/10.1109/BIBE.2010.12
Xanthopoulos P, Rebennack S, Liu CC, Zhang J, Holmes GL, Uthman BM et al. A novel wavelet based algorithm for spike and wave detection in absence epilepsy. In 10th IEEE International Conference on Bioinformatics and Bioengineering 2010, BIBE 2010. 2010. p. 14-19. 5521720 https://doi.org/10.1109/BIBE.2010.12
Xanthopoulos, Petros ; Rebennack, Steffen ; Liu, Chang Chia ; Zhang, Jicong ; Holmes, Gregory L. ; Uthman, Basim M. ; Pardalos, Panos M. / A novel wavelet based algorithm for spike and wave detection in absence epilepsy. 10th IEEE International Conference on Bioinformatics and Bioengineering 2010, BIBE 2010. 2010. pp. 14-19
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