A novel score to estimate the risk of pneumonia after cardiac surgery

Arman Kilic, Rika Ohkuma, Joshua C. Grimm, J. Trent Magruder, Marc S Sussman, Eric B. Schneider, Glenn Whitman

Research output: Contribution to journalArticle

Abstract

Objective The purpose of this study was to derive and validate a risk score for pneumonia (PNA) after cardiac surgery. Methods Adults undergoing cardiac surgery between 2005 and 2012 were identified in a single-institution database. The primary outcome was postoperative PNA. Patients were randomly assigned to training and validation sets in a 3:1 ratio. A multivariable model was constructed incorporating univariate pre- and intraoperative predictors of PNA in the training set. Points were assigned to significant risk factors in the multivariable model based on their associated regression coefficients. Results A total of 6222 patients were included. The overall rate of postoperative PNA was 4.5% (n = 282). A 33-point score incorporating 6 risk factors (age, chronic lung disease, peripheral vascular disease, cardiopulmonary bypass time, intraoperative red blood cell transfusion, and pre- or intraoperative intra-aortic balloon pump) was generated. The model used to generate the score in the training set was robust in predicting PNA (c = 0.72, P

Original languageEnglish (US)
Pages (from-to)1415-1421
Number of pages7
JournalJournal of Thoracic and Cardiovascular Surgery
Volume151
Issue number5
DOIs
StatePublished - May 1 2016

Fingerprint

Thoracic Surgery
Pneumonia
Erythrocyte Transfusion
Peripheral Vascular Diseases
Cardiopulmonary Bypass
Lung Diseases
Chronic Disease
Databases

Keywords

  • outcomes
  • pneumonia
  • postoperative complications
  • risk score

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine

Cite this

A novel score to estimate the risk of pneumonia after cardiac surgery. / Kilic, Arman; Ohkuma, Rika; Grimm, Joshua C.; Magruder, J. Trent; Sussman, Marc S; Schneider, Eric B.; Whitman, Glenn.

In: Journal of Thoracic and Cardiovascular Surgery, Vol. 151, No. 5, 01.05.2016, p. 1415-1421.

Research output: Contribution to journalArticle

Kilic, Arman ; Ohkuma, Rika ; Grimm, Joshua C. ; Magruder, J. Trent ; Sussman, Marc S ; Schneider, Eric B. ; Whitman, Glenn. / A novel score to estimate the risk of pneumonia after cardiac surgery. In: Journal of Thoracic and Cardiovascular Surgery. 2016 ; Vol. 151, No. 5. pp. 1415-1421.
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