A novel mutation of STK11/LKB1 gene leads to the loss of cell growth inhibition in head and neck squamous cell carcinoma

Medicine & Life Sciences

• Protein-Serine-Threonine Kinases 100%
• Squamous Cell Carcinoma of Head and Neck 99%
• Mutation 50%
• Growth 45%
• Genes 36%
• Point Mutation 19%
• Phosphotransferases 15%
• Carcinogenesis 15%
• Loss of Heterozygosity 11%
• Threonine 11%
• Amino Acid Substitution 10%
• Mutation Rate 10%
• Missense Mutation 10%
• Alanine 10%
• Tumor Suppressor Genes 9%
• Catalytic Domain 8%
• Exons 8%
• Nucleotides 8%
• Proteins 7%
• Gene Expression 5%
• Cell Line 5%