A novel fluorophore based on the coupling of AIE and ESIPT mechanisms and its application in biothiol imaging

Qing Chen, Chunman Jia, Yinfeng Zhang, Wei Du, Yile Wang, Yan Huang, Qiuyun Yang, Qi Zhang

Research output: Contribution to journalArticle


A novel fluorophore TPE-HBT was designed based on the intersection of tetraphenylethene (TPE) and 2-(2′-hydroxyphenyl)benzothiazole (HBT). Owing to the synergistic effect of aggregation-induced emission (AIE) and excited-state intramolecular proton transfer (ESIPT) mechanisms, this fluorophore exhibits excellent performance with a high solid-state fluorescence quantum yield (ΦF = 0.97) and a large Stokes shift (>200 nm). Moreover, its simple modification with the 2,4-dinitrobenzenesulfonyl group makes it suitable for biothiol imaging.

Original languageEnglish (US)
Pages (from-to)7736-7742
Number of pages7
JournalJournal of Materials Chemistry B
Issue number37
Publication statusPublished - Jan 1 2017


ASJC Scopus subject areas

  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)

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