TY - JOUR
T1 - A Novel Assessment Tool for Impulsive Aggression in Children with Attention-Deficit/Hyperactivity Disorder
AU - Ceresoli-Borroni, Gianpiera
AU - Liranso, Tesfaye
AU - Brittain, Scott T.
AU - Connor, Daniel F.
AU - Evans, Christopher J.
AU - Findling, Robert L.
AU - Hwang, Steve
AU - Candler, Shawn A.
AU - Robb, Adelaide S.
AU - Nasser, Azmi
AU - Schwabe, Stefan
N1 - Funding Information:
This study was funded by Supernus Pharmaceuticals, Inc., Current employees of Supernus (G.C.-B., T.L., S.A.C., A.N., and S.S.) are authors on this article. S.T.B. was an employee of Supernus at the time this work was conducted. C.J.E. and S.H. were paid consultants to Supernus at the time this work was conducted. Editorial support was provided by IMPRINT Science, New York, NY, and was funded by Supernus Pharmaceuticals, Inc.
Funding Information:
Editorial support was provided by IMPRINT Science, New York, NY, and was funded by Supernus Pharmaceuticals, Inc.
Funding Information:
Funding: This study was funded by Supernus Pharmaceuticals, Inc., Current employees of Supernus (G.C.-B., T.L., S.A.C., A.N., and S.S.) are authors on this article. S.T.B. was an employee of Supernus at the time this work was conducted. C.J.E. and S.H. were paid consultants to Supernus at the time this work was conducted.
Publisher Copyright:
© Gianpiera Ceresoli-Borroni et al. 2019; Published by Mary Ann Liebert, Inc.
PY - 2019/10
Y1 - 2019/10
N2 - Objective: To establish the validity and reliability of a provisional 30-item impulsive aggression (IA) diary in children (ages 6-12 years, inclusive) with attention-deficit/hyperactivity disorder (ADHD). Methods: The provisional 30-item IA diary was administered for 14 days to parents of children with ADHD and IA symptoms (n = 103). Key inclusion criteria: confirmed ADHD diagnosis; signs of IA as measured by a Retrospective-Modified Overt Aggression Scale (R-MOAS) score ≥20 and an Aggression Questionnaire score of -2 to -5. Analyses included inter-item correlations, exploratory factor analysis (EFA), item response theory (IRT) modeling, internal consistency, test-retest reliability (TRT), concurrent validity (estimated by correlation between the IA diary and the R-MOAS/Nisonger Child Behavior Rating Form), and known-groups methods. Results: The prevalence rates of 15 (50.0%) items were found to be too low (<1%) for analysis; three items with prevalence rates ≤1% were retained, as content validity was deemed high by clinical experts. The remaining 12 behavior items had prevalence rates of 2.7%-73.6%. EFA and IRT models confirmed two subdomains in the IA diary included within a general domain of IA behavior frequency, yielding a single total behavioral frequency score (TBFS). Internal consistency was high for this TBFS (marginal reliability = 0.86 and α = 0.73). TRT for the TBFS, based on the intraclass correlation coefficient, was 0.8. Concurrent validity of TBFS with R-MOAS ranged from r = 0.49 to r = 0.62. Conclusion: The final 15-item IA diary is a reliable, psychometrically validated IA measurement tool that will allow clinicians and researchers to assess the frequency of IA behavior.
AB - Objective: To establish the validity and reliability of a provisional 30-item impulsive aggression (IA) diary in children (ages 6-12 years, inclusive) with attention-deficit/hyperactivity disorder (ADHD). Methods: The provisional 30-item IA diary was administered for 14 days to parents of children with ADHD and IA symptoms (n = 103). Key inclusion criteria: confirmed ADHD diagnosis; signs of IA as measured by a Retrospective-Modified Overt Aggression Scale (R-MOAS) score ≥20 and an Aggression Questionnaire score of -2 to -5. Analyses included inter-item correlations, exploratory factor analysis (EFA), item response theory (IRT) modeling, internal consistency, test-retest reliability (TRT), concurrent validity (estimated by correlation between the IA diary and the R-MOAS/Nisonger Child Behavior Rating Form), and known-groups methods. Results: The prevalence rates of 15 (50.0%) items were found to be too low (<1%) for analysis; three items with prevalence rates ≤1% were retained, as content validity was deemed high by clinical experts. The remaining 12 behavior items had prevalence rates of 2.7%-73.6%. EFA and IRT models confirmed two subdomains in the IA diary included within a general domain of IA behavior frequency, yielding a single total behavioral frequency score (TBFS). Internal consistency was high for this TBFS (marginal reliability = 0.86 and α = 0.73). TRT for the TBFS, based on the intraclass correlation coefficient, was 0.8. Concurrent validity of TBFS with R-MOAS ranged from r = 0.49 to r = 0.62. Conclusion: The final 15-item IA diary is a reliable, psychometrically validated IA measurement tool that will allow clinicians and researchers to assess the frequency of IA behavior.
KW - aggression
KW - assessment tool
KW - attention-deficit/hyperactivity disorder
KW - impulsive aggression diary
KW - psychometrics
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U2 - 10.1089/cap.2019.0035
DO - 10.1089/cap.2019.0035
M3 - Article
C2 - 31369291
AN - SCOPUS:85072994704
SN - 1044-5463
VL - 29
SP - 592
EP - 598
JO - Journal of child and adolescent psychopharmacology
JF - Journal of child and adolescent psychopharmacology
IS - 8
ER -