This report describes a new familial syndrome characterized by a combination of bone marrow failure and chronic liver disease. This disorder appears to be genetic in origin with an autosomal dominant inheritance and was characterized by hyperactivity of the immune system with increased activated cytotoxic T lymphocytes in peripheral blood and bone marrow and the presence of γ-interferon messenger RNA in bone marrow of several cases.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Feb 1997|
- Activated cytotoxic T lymphocytes
- Bone marrow failure
- Chronic liver disease
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