A new syndrome of familial aplastic anemia and chronic liver disease

Muzaffar H. Qazilbash; Johnson M. Liu; Adrianna Vlachos; Stephen Fruchtman; Hans Messner; Alvin Zipursky; Blanche P. Alter; Neal S. Young

A new syndrome of familial aplastic anemia and chronic liver disease

Muzaffar H. Qazilbash, Johnson M. Liu, Adrianna Vlachos, Stephen Fruchtman, Hans Messner, Alvin Zipursky, Blanche P. Alter, Neal S. Young

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

This report describes a new familial syndrome characterized by a combination of bone marrow failure and chronic liver disease. This disorder appears to be genetic in origin with an autosomal dominant inheritance and was characterized by hyperactivity of the immune system with increased activated cytotoxic T lymphocytes in peripheral blood and bone marrow and the presence of γ-interferon messenger RNA in bone marrow of several cases.

Original language	English (US)
Pages (from-to)	164-167
Number of pages	4
Journal	Acta Haematologica
Volume	97
Issue number	3
State	Published - Feb 1997
Externally published	Yes

Keywords

γ-interferon
Activated cytotoxic T lymphocytes
Bone marrow failure
Chronic liver disease

ASJC Scopus subject areas

Hematology

Cite this

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title = "A new syndrome of familial aplastic anemia and chronic liver disease",

abstract = "This report describes a new familial syndrome characterized by a combination of bone marrow failure and chronic liver disease. This disorder appears to be genetic in origin with an autosomal dominant inheritance and was characterized by hyperactivity of the immune system with increased activated cytotoxic T lymphocytes in peripheral blood and bone marrow and the presence of γ-interferon messenger RNA in bone marrow of several cases.",

keywords = "γ-interferon, Activated cytotoxic T lymphocytes, Bone marrow failure, Chronic liver disease",

author = "Qazilbash, {Muzaffar H.} and Liu, {Johnson M.} and Adrianna Vlachos and Stephen Fruchtman and Hans Messner and Alvin Zipursky and Alter, {Blanche P.} and Young, {Neal S.}",

year = "1997",

month = feb,

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T1 - A new syndrome of familial aplastic anemia and chronic liver disease

AU - Qazilbash, Muzaffar H.

AU - Liu, Johnson M.

AU - Vlachos, Adrianna

AU - Fruchtman, Stephen

AU - Messner, Hans

AU - Zipursky, Alvin

AU - Alter, Blanche P.

AU - Young, Neal S.

PY - 1997/2

Y1 - 1997/2

N2 - This report describes a new familial syndrome characterized by a combination of bone marrow failure and chronic liver disease. This disorder appears to be genetic in origin with an autosomal dominant inheritance and was characterized by hyperactivity of the immune system with increased activated cytotoxic T lymphocytes in peripheral blood and bone marrow and the presence of γ-interferon messenger RNA in bone marrow of several cases.

AB - This report describes a new familial syndrome characterized by a combination of bone marrow failure and chronic liver disease. This disorder appears to be genetic in origin with an autosomal dominant inheritance and was characterized by hyperactivity of the immune system with increased activated cytotoxic T lymphocytes in peripheral blood and bone marrow and the presence of γ-interferon messenger RNA in bone marrow of several cases.

KW - γ-interferon

KW - Activated cytotoxic T lymphocytes

KW - Bone marrow failure

KW - Chronic liver disease

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AN - SCOPUS:0031013936

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JF - Acta Haematologica

IS - 3

ER -

A new syndrome of familial aplastic anemia and chronic liver disease

Abstract

Keywords

ASJC Scopus subject areas

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