A new method to assess metastatic potential of human prostate cancer

Relative nuclear roundness

D. A. Diamond, S. J. Berry, H. J. Jewett, J. C. Eggleston, D. S. Coffey

Research output: Contribution to journalArticle

Abstract

A new technique has been developed that helped in an accurate prediction of the prognosis of 27 patients with stages B1 and B2 prostatic cancer following radical prostatectomy. This method involves computer-assisted analysis of histological specimens of the primary lesion removed at the time of radical perineal prostatectomy. On the basis of a nuclear shape factor, known as nuclear roundness, we have been able to distinguish those tumors with a high metastatic potential from tumors that are less aggressive. This technique provides pathologists with quantitative information about the metastatic potential of a tumor, which may aid in the management of the individual patient.

Original languageEnglish (US)
Pages (from-to)729-734
Number of pages6
JournalJournal of Urology
Volume128
Issue number4
StatePublished - 1982
Externally publishedYes

Fingerprint

Prostatic Neoplasms
Prostatectomy
Neoplasms
Pathologists

ASJC Scopus subject areas

  • Urology

Cite this

Diamond, D. A., Berry, S. J., Jewett, H. J., Eggleston, J. C., & Coffey, D. S. (1982). A new method to assess metastatic potential of human prostate cancer: Relative nuclear roundness. Journal of Urology, 128(4), 729-734.

A new method to assess metastatic potential of human prostate cancer : Relative nuclear roundness. / Diamond, D. A.; Berry, S. J.; Jewett, H. J.; Eggleston, J. C.; Coffey, D. S.

In: Journal of Urology, Vol. 128, No. 4, 1982, p. 729-734.

Research output: Contribution to journalArticle

Diamond, DA, Berry, SJ, Jewett, HJ, Eggleston, JC & Coffey, DS 1982, 'A new method to assess metastatic potential of human prostate cancer: Relative nuclear roundness', Journal of Urology, vol. 128, no. 4, pp. 729-734.
Diamond DA, Berry SJ, Jewett HJ, Eggleston JC, Coffey DS. A new method to assess metastatic potential of human prostate cancer: Relative nuclear roundness. Journal of Urology. 1982;128(4):729-734.
Diamond, D. A. ; Berry, S. J. ; Jewett, H. J. ; Eggleston, J. C. ; Coffey, D. S. / A new method to assess metastatic potential of human prostate cancer : Relative nuclear roundness. In: Journal of Urology. 1982 ; Vol. 128, No. 4. pp. 729-734.
@article{58debef34da24fdfbb62e778ca92679b,
title = "A new method to assess metastatic potential of human prostate cancer: Relative nuclear roundness",
abstract = "A new technique has been developed that helped in an accurate prediction of the prognosis of 27 patients with stages B1 and B2 prostatic cancer following radical prostatectomy. This method involves computer-assisted analysis of histological specimens of the primary lesion removed at the time of radical perineal prostatectomy. On the basis of a nuclear shape factor, known as nuclear roundness, we have been able to distinguish those tumors with a high metastatic potential from tumors that are less aggressive. This technique provides pathologists with quantitative information about the metastatic potential of a tumor, which may aid in the management of the individual patient.",
author = "Diamond, {D. A.} and Berry, {S. J.} and Jewett, {H. J.} and Eggleston, {J. C.} and Coffey, {D. S.}",
year = "1982",
language = "English (US)",
volume = "128",
pages = "729--734",
journal = "Journal of Urology",
issn = "0022-5347",
publisher = "Elsevier Inc.",
number = "4",

}

TY - JOUR

T1 - A new method to assess metastatic potential of human prostate cancer

T2 - Relative nuclear roundness

AU - Diamond, D. A.

AU - Berry, S. J.

AU - Jewett, H. J.

AU - Eggleston, J. C.

AU - Coffey, D. S.

PY - 1982

Y1 - 1982

N2 - A new technique has been developed that helped in an accurate prediction of the prognosis of 27 patients with stages B1 and B2 prostatic cancer following radical prostatectomy. This method involves computer-assisted analysis of histological specimens of the primary lesion removed at the time of radical perineal prostatectomy. On the basis of a nuclear shape factor, known as nuclear roundness, we have been able to distinguish those tumors with a high metastatic potential from tumors that are less aggressive. This technique provides pathologists with quantitative information about the metastatic potential of a tumor, which may aid in the management of the individual patient.

AB - A new technique has been developed that helped in an accurate prediction of the prognosis of 27 patients with stages B1 and B2 prostatic cancer following radical prostatectomy. This method involves computer-assisted analysis of histological specimens of the primary lesion removed at the time of radical perineal prostatectomy. On the basis of a nuclear shape factor, known as nuclear roundness, we have been able to distinguish those tumors with a high metastatic potential from tumors that are less aggressive. This technique provides pathologists with quantitative information about the metastatic potential of a tumor, which may aid in the management of the individual patient.

UR - http://www.scopus.com/inward/record.url?scp=0020381911&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020381911&partnerID=8YFLogxK

M3 - Article

VL - 128

SP - 729

EP - 734

JO - Journal of Urology

JF - Journal of Urology

SN - 0022-5347

IS - 4

ER -