A new lipase in regulating lipid mobilization: Hormone-sensitive lipase is not alone

Daniel M. Raben, Joseph J. Baldassare

Research output: Contribution to journalShort surveypeer-review

Abstract

Three papers recently appeared simultaneously that identify a new triacylglycerol lipase. Zimmerman et al. identified this lipase as adipocyte triacylglycerol lipase (ATGL). Jenkins et al. identified it as the ζ-isoform of a calcium-independent phospholipase A2 (iPLA 2), whereas Villena et al. found this enzyme and called it desnutrin. Interestingly, if, as implied, this lipase works in concert with hormone-sensitive lipase, then our concept of regulated fatty acid mobilization from triacylglycerols will have to be revised.

Original languageEnglish (US)
Pages (from-to)35-36
Number of pages2
JournalTrends in Endocrinology and Metabolism
Volume16
Issue number2
DOIs
StatePublished - Mar 2005

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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