A new de novo approach for optimizing peptides that inhibit HIV-1 entry

Ho Ki Fung, Christodoulos A. Floudas, Martin S. Taylor, Robert F.Siliciano

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A new de novo protein design framework and its application to the redesign of an HIV-1 entry peptide inhibitor is presented.

Original languageEnglish (US)
Title of host publication17th European Symposium on Computer Aided Process Engineering
EditorsValentin Plesu, Paul Serban Agachi
Pages959-964
Number of pages6
DOIs
StatePublished - Dec 1 2007

Publication series

NameComputer Aided Chemical Engineering
Volume24
ISSN (Print)1570-7946

Keywords

  • Drug design
  • In silico sequence selection
  • Peptide and protein design and discovery
  • de novo protein design
  • optimization
  • structure prediction

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Computer Science Applications

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