A new approach for optical assessment of directional anisotropy in turbid media

Pejhman Ghassemi, Lauren T. Moffatt, Jeffrey W. Shupp, Jessica C. Ramella-Roman

Research output: Contribution to journalArticlepeer-review

Abstract

A study of polarized light transport in scattering media exhibiting directional anisotropy or linear birefringence is presented in this paper. Novel theoretical and experimental methodologies for the quantification of birefringent alignment based on out-of-plane polarized light transport are presented here. A polarized Monte Carlo model and a polarimetric imaging system were devised to predict and measure the impact of birefringence on an impinging linearly polarized light beam. Ex-vivo experiments conducted on bovine tendon, a biological sample consisting of highly packed type I collagen fibers with birefringent property, showed good agreement with the analytical results. Top view geometry of the in-plane (a) and the out-of-plane (b) detection. Letter C indicates the location of the detection arm. A study of polarized light transport in scattering media exhibiting directional anisotropy or linear birefringence is presented. Novel theoretical and experimental methodologies for the quantification of birefringent alignment based on out-of-plane polarized light transport are demonstrated. A polarized Monte Carlo model and a polarimetric imaging system were devised to predict and measure the impact of birefringence on an impinging linearly polarized light beam. Ex-vivo experiments conducted on bovine tendon showed good agreement with the analytical results.

Original languageEnglish (US)
Pages (from-to)100-108
Number of pages9
JournalJournal of Biophotonics
Volume9
Issue number1-2
DOIs
StatePublished - Jan 1 2016
Externally publishedYes

Keywords

  • Birefringence
  • Directional anisotropy
  • Monte Carlo
  • Out-of-plane
  • Polarized light imaging

ASJC Scopus subject areas

  • Materials Science(all)
  • Engineering(all)
  • Physics and Astronomy(all)
  • Chemistry(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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