A neurosurgeon's guide to stem cells, cancer stem cells, and brain tumor stem cells

Samuel H. Cheshier; M. Yashar S. Kalani; Michael Lim; Laurie Ailles; Steven L. Huhn; Irving L. Weissman

doi:10.1227/01.NEU.0000349921.14519.2A

A neurosurgeon's guide to stem cells, cancer stem cells, and brain tumor stem cells

Samuel H. Cheshier, M. Yashar S. Kalani, Michael Lim, Laurie Ailles, Steven L. Huhn, Irving L. Weissman

School of Medicine

Research output: Contribution to journal › Review article › peer-review

32 Scopus citations

Abstract

STEM CELLS AND their potential applications have become the forefront of scientific, political, and ethical discourse. Whereas stem cells were long accepted as units of development and evolution, it is now becoming increasingly clear that they are also units of oncogenesis. Although the field of stem cell biology is expanding at an astounding rate, the data attained are not readily translatable for the physicians who may eventually deliver these tools to patients. Herein, we provide a brief review of stem cell and cancer stem cell biology and highlight the scientific and clinical implications of recent findings regarding the presence of cancer-forming stem cells in brain tumors.

Original language	English (US)
Pages (from-to)	237-249
Number of pages	13
Journal	Neurosurgery
Volume	65
Issue number	2
DOIs	https://doi.org/10.1227/01.NEU.0000349921.14519.2A
State	Published - Aug 1 2009

Keywords

Brain tumor
Brain tumor stem cell
Cancer stem cell
Stem cell

ASJC Scopus subject areas

Surgery
Clinical Neurology

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10.1227/01.NEU.0000349921.14519.2A

Cite this

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abstract = "STEM CELLS AND their potential applications have become the forefront of scientific, political, and ethical discourse. Whereas stem cells were long accepted as units of development and evolution, it is now becoming increasingly clear that they are also units of oncogenesis. Although the field of stem cell biology is expanding at an astounding rate, the data attained are not readily translatable for the physicians who may eventually deliver these tools to patients. Herein, we provide a brief review of stem cell and cancer stem cell biology and highlight the scientific and clinical implications of recent findings regarding the presence of cancer-forming stem cells in brain tumors.",

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AU - Huhn, Steven L.

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A neurosurgeon's guide to stem cells, cancer stem cells, and brain tumor stem cells

Abstract

Keywords

ASJC Scopus subject areas

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