A nanobiological approach to nanotoxicology

J. F. Nyland, E. K. Silbergeld

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


There is an urgent need to develop efficient and rapid strategies in order to characterize the potential health risks associated with nanomaterials, given the speed with which applications and uses are increasing. Use of standard toxicity methods will not be sufficient to meet this need. This article proposes the adoption of two novel guidances: the system™s biological approach to toxicity testing advocated by the US National Research Council and a nanobiological perspective that identifies key events at the nanoscale that are relevant to signal transduction and structural biology.

Original languageEnglish (US)
Pages (from-to)393-400
Number of pages8
JournalHuman and Experimental Toxicology
Issue number6-7
StatePublished - Jun 2009


  • Molecular biology
  • Nanomaterial
  • Toxicology

ASJC Scopus subject areas

  • Toxicology
  • Health, Toxicology and Mutagenesis


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