A mutant of Mycobacterium smegmatis defective in dipeptide transport

Achal Bhatt; Renee Green; Roswell Coles; Michael Condon; Nancy D. Connell

doi:10.1128/jb.180.24.6773-6775.1998

A mutant of Mycobacterium smegmatis defective in dipeptide transport

Achal Bhatt, Renee Green, Roswell Coles, Michael Condon, Nancy D. Connell

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A mutant of Mycobacterium smegmatis unable to use the dipeptide carnosine (β-alanyl-L-histidine) as a sole carbon or nitrogen source was isolated. Carnosinase activity and the ability to grow on β-Ala and/or L- His were similar in the mutant and the wild type. However, the mutant showed significant impairment in the uptake of camosine. This study is the first description of a peptide utilization mutant of a mycobacterium.

Original language	English (US)
Pages (from-to)	6773-6775
Number of pages	3
Journal	Journal of bacteriology
Volume	180
Issue number	24
DOIs	https://doi.org/10.1128/jb.180.24.6773-6775.1998
State	Published - Dec 1998
Externally published	Yes

ASJC Scopus subject areas

Microbiology
Molecular Biology

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10.1128/jb.180.24.6773-6775.1998

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abstract = "A mutant of Mycobacterium smegmatis unable to use the dipeptide carnosine (β-alanyl-L-histidine) as a sole carbon or nitrogen source was isolated. Carnosinase activity and the ability to grow on β-Ala and/or L- His were similar in the mutant and the wild type. However, the mutant showed significant impairment in the uptake of camosine. This study is the first description of a peptide utilization mutant of a mycobacterium.",

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AU - Bhatt, Achal

AU - Green, Renee

AU - Coles, Roswell

AU - Condon, Michael

AU - Connell, Nancy D.

PY - 1998/12

Y1 - 1998/12

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AB - A mutant of Mycobacterium smegmatis unable to use the dipeptide carnosine (β-alanyl-L-histidine) as a sole carbon or nitrogen source was isolated. Carnosinase activity and the ability to grow on β-Ala and/or L- His were similar in the mutant and the wild type. However, the mutant showed significant impairment in the uptake of camosine. This study is the first description of a peptide utilization mutant of a mycobacterium.

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JF - Journal of bacteriology

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A mutant of Mycobacterium smegmatis defective in dipeptide transport

Abstract

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